ArticleNature communications2023
Neural control of lexical tone production in human laryngeal motor cortex.
Article in Nature communications, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07460037 (Investigation of Chinese-Specific Speech Imagery Encoding and Decoding Using High-Density Electrocorticography), which is not on this map. Cited by 16 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Investigation of Chinese-Specific Speech Imagery Encoding and Decoding Using High-Density Electrocorticography
Who cites it
16 citing papers in PubMed, 24 citations in OpenAlex.
- A neural architecture for imagined and overt speech motor dynamics.Nature neuroscience · 2026Article
- A Fine-grained Spatiotemporal ECoG Dataset during Speech Perception in Tonal Language.Scientific data · 2026Article
- Encoding of speech modes and loudness in ventral precentral gyrus.Nature communications · 2026Article
- Electrical Cortical Stimulation for Language Mapping in Epilepsy Surgery-A Systematic Review.Brain sciences · 2025Review
- Real-time decoding of full-spectrum Chinese using brain-computer interface.Science advances · 2025Article
- Speaking in Tones: The role of lexical tones in Chinese-speaking Primary Progressive Aphasia.medRxiv : the preprint server for health sciences · 2025Article
- An instantaneous voice-synthesis neuroprosthesis.Nature · 2025Article
- Causal Lesion Evidence for Two Motor Speech Coordination Networks in the Brain.bioRxiv : the preprint server for biology · 2025Article
- Encoding of speech modes and loudness in ventral precentral gyrus.bioRxiv : the preprint server for biology · 2025Article
- Article
- Acoustic Inspired Brain-to-Sentence Decoder for Logosyllabic Language.Cyborg and bionic systems (Washington, D.C.) · 2025Article
- The cost of language: functionally over-dominant language circuits in the human brain may limit cognitive abilities and non-verbal executive functions.Frontiers in human neuroscience · 2025Article
- An instantaneous voice synthesis neuroprosthesis.bioRxiv : the preprint server for biology · 2024Article
- The speech neuroprosthesis.Nature reviews. Neuroscience · 2024Review
- Knowns and unknowns about the neurobiology of stuttering.PLoS biology · 2024Article
- The ethical significance of user-control in AI-driven speech-BCIs: a narrative review.Frontiers in human neuroscience · 2024Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 3 institutions in 2 countries.
Funding
Abstract
In tonal languages, which are spoken by nearly one-third of the world's population, speakers precisely control the tension of vocal folds in the larynx to modulate pitch in order to distinguish words with completely different meanings. The specific pitch trajectories for a given tonal language are called lexical tones. Here, we used high-density direct cortical recordings to determine the neural basis of lexical tone production in native Mandarin-speaking participants. We found that instead of a tone category-selective coding, local populations in the bilateral laryngeal motor cortex (LMC) encode articulatory kinematic information to generate the pitch dynamics of lexical tones. Using a computational model of tone production, we discovered two distinct patterns of population activity in LMC commanding pitch rising and lowering. Finally, we showed that direct electrocortical stimulation of different local populations in LMC evoked pitch rising and lowering during tone production, respectively. Together, these results reveal the neural basis of vocal pitch control of lexical tones in tonal languages.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.