Evidence map›Paper›PMID 37903778›Full record

ArticleNature communications2023

Leveraging data from the Genomes-to-Fields Initiative to investigate genotype-by-environment interactions in maize in North America.

Marco Lopez-Cruz, Fernando M Aguate, Jacob D Washburn, Natalia de Leon, Shawn M Kaeppler, Dayane Cristina Lima, Ruijuan Tan, Addie Thompson, Laurence Willard De La Bretonne, Gustavo de Los Campos

Abstract read
In one paragraph

Article in Nature communications, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed.

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  11. Order from entropy: big data from FAIR data cohorts in the digital age of plant breeding.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2025
    Review
  12. Article
  13. Breeding perspectives on tackling trait genome-to-phenome (G2P) dimensionality using ensemble-based genomic prediction.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2025
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Marco Lopez-CruzDepartment of Epidemiology and Biostatistics, Michigan State University, East Lansing, MI, 48824, USA. lopezcru@msu.edu.ORCID 0000-0002-2548-1766
Fernando M AguateDepartment of Epidemiology and Biostatistics, Michigan State University, East Lansing, MI, 48824, USA.
Jacob D WashburnUnited States Department of Agriculture, Agricultural Research Service, University of Missouri, Columbia, MO, 65211, USA.
Natalia de LeonDepartment of Agronomy, University of Wisconsin, Madison, WI, 53706, USA.
Shawn M KaepplerDepartment of Agronomy, University of Wisconsin, Madison, WI, 53706, USA.
Dayane Cristina LimaDepartment of Agronomy, University of Wisconsin, Madison, WI, 53706, USA.ORCID 0000-0002-5327-2160
Ruijuan TanDepartment of Plant, Soil and Microbial Sciences, Michigan State University, East Lansing, MI, 48824, USA.
Addie ThompsonDepartment of Plant, Soil and Microbial Sciences, Michigan State University, East Lansing, MI, 48824, USA.ORCID 0000-0002-4442-6578
Laurence Willard De La BretonneDepartment of Agronomy, University of Wisconsin, Madison, WI, 53706, USA.
Gustavo de Los CamposDepartment of Epidemiology and Biostatistics, Michigan State University, East Lansing, MI, 48824, USA. gustavoc@msu.edu.ORCID 0000-0001-5692-7129

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Genotype-by-environment (G×E) interactions can significantly affect crop performance and stability. Investigating G×E requires extensive data sets with diverse cultivars tested over multiple locations and years. The Genomes-to-Fields (G2F) Initiative has tested maize hybrids in more than 130 year-locations in North America since 2014. Here, we curate and expand this data set by generating environmental covariates (using a crop model) for each of the trials. The resulting data set includes DNA genotypes and environmental data linked to more than 70,000 phenotypic records of grain yield and flowering traits for more than 4000 hybrids. We show how this valuable data set can serve as a benchmark in agricultural modeling and prediction, paving the way for countless G×E investigations in maize. We use multivariate analyses to characterize the data set's genetic and environmental structure, study the association of key environmental factors with traits, and provide benchmarks using genomic prediction models.

Indexed as

Gene-Environment InteractionZea maysGenomicsGenotypePhenotype

Identifiers

PMID37903778
PMCPMC10616096

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.