Evidence map›Paper›PMID 37903625›Full record

ArticleLife science alliance2024

Biogenesis, inheritance, and 3D ultrastructure of the microsporidian mitosome.

Christian Hacker, Kacper Sendra, Priyanka Keisham, Teodora Filipescu, James Lucocq, Fatemeh Salimi, Sophie Ferguson, David Bhella, Stuart A MacNeill, Martin Embley and 1 more

Open access · goldAbstract read
In one paragraph

Article in Life science alliance, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.7field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Cryo-ET reveals the in situ architecture of the polar tube invasion apparatus from microsporidian parasites.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  3. Article
  4. Treatment of MicrosporidiumMicroorganisms · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Christian HackerSchool of Medicine, University of St Andrews, St Andrews, UK.
Kacper SendraBiosciences Institute, The Medical School, Catherine Cookson Building, Newcastle University, Newcastle upon Tyne, UK.
Priyanka KeishamSchool of Medicine, University of St Andrews, St Andrews, UK.
Teodora FilipescuSchool of Medicine, University of St Andrews, St Andrews, UK.
James LucocqDepartment of Surgery, Dundee Medical School Ninewells Hospital, Dundee, UK jmlucocq@gmail.com.
Fatemeh SalimiSchool of Medicine, University of St Andrews, St Andrews, UK.
Sophie FergusonSchool of Medicine, University of St Andrews, St Andrews, UK.
David BhellaMRC-University of Glasgow Centre for Virus Research, Glasgow, UK.
Stuart A MacNeillSchool of Biology, University of St Andrews, St Andrews, UK.
Martin EmbleyBiosciences Institute, Centre for Bacterial Cell Biology, Baddiley-Clark Building, Newcastle University, Newcastle upon Tyne, UK.
John LucocqSchool of Medicine, University of St Andrews, St Andrews, UK.ORCID https://orcid.org/0000-0002-5191-0093
University of St Andrews · GBNewcastle University · GBMRC University of Glasgow Centre for Virus Research · GB

Funding

Wellcome Trust
6 · The paper itself

Abstract

During the reductive evolution of obligate intracellular parasites called microsporidia, a tiny remnant mitochondrion (mitosome) lost its typical cristae, organellar genome, and most canonical functions. Here, we combine electron tomography, stereology, immunofluorescence microscopy, and bioinformatics to characterise mechanisms of growth, division, and inheritance of this minimal mitochondrion in two microsporidia species (grown within a mammalian RK13 culture-cell host). Mitosomes of

Indexed as

Fungal ProteinsMicrosporidiaAnimalsDynaminsMammalsMitochondriaQuinazolinonesSaccharomyces cerevisiae3-(2,4-dichloro-5-methoxyphenyl)-2-sulfanyl-4(3H)-quinazolinoneDynaminsFungal ProteinsQuinazolinones

Identifiers

PMID37903625
PMCPMC10618108
OpenAlexW4388033327

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.