Evidence map›Paper›PMID 37903505›Full record

ArticleACS nano2023

Nanomechanical Sensing for Mass Flow Control in Nanowire-Based Open Nanofluidic Systems.

Javier E Escobar, Juan Molina, Eduardo Gil-Santos, José J Ruz, Óscar Malvar, Priscila M Kosaka, Javier Tamayo, Álvaro San Paulo, Montserrat Calleja

Open access · hybridAbstract read
In one paragraph

Article in ACS nano, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
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  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Javier E EscobarInstituto de Micro y Nanotecnología (IMN-CNM, CSIC), Isaac Newton 8, 28760 Tres Cantos, Madrid, Spain.
Juan MolinaInstituto de Micro y Nanotecnología (IMN-CNM, CSIC), Isaac Newton 8, 28760 Tres Cantos, Madrid, Spain.
Eduardo Gil-SantosInstituto de Micro y Nanotecnología (IMN-CNM, CSIC), Isaac Newton 8, 28760 Tres Cantos, Madrid, Spain.ORCID 0000-0002-7100-934X
José J RuzInstituto de Micro y Nanotecnología (IMN-CNM, CSIC), Isaac Newton 8, 28760 Tres Cantos, Madrid, Spain.ORCID 0000-0003-4604-7042
Óscar MalvarInstituto de Micro y Nanotecnología (IMN-CNM, CSIC), Isaac Newton 8, 28760 Tres Cantos, Madrid, Spain.ORCID 0000-0001-9860-0634
Priscila M KosakaInstituto de Micro y Nanotecnología (IMN-CNM, CSIC), Isaac Newton 8, 28760 Tres Cantos, Madrid, Spain.
Javier TamayoInstituto de Micro y Nanotecnología (IMN-CNM, CSIC), Isaac Newton 8, 28760 Tres Cantos, Madrid, Spain.
Álvaro San PauloInstituto de Micro y Nanotecnología (IMN-CNM, CSIC), Isaac Newton 8, 28760 Tres Cantos, Madrid, Spain.ORCID 0000-0001-9325-8892
Montserrat CallejaInstituto de Micro y Nanotecnología (IMN-CNM, CSIC), Isaac Newton 8, 28760 Tres Cantos, Madrid, Spain.ORCID 0000-0003-2414-5725
Institute of Micro and Nanotechnology · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Open nanofluidic systems, where liquids flow along the outer surface of nanoscale structures, provide otherwise unfeasible capabilities for extremely miniaturized liquid handling applications. A critical step toward fully functional applications is to obtain quantitative mass flow control. We demonstrate the application of nanomechanical sensing for this purpose by integrating voltage-driven liquid flow along nanowire open channels with mass detection based on flexural resonators. This approach is validated by assembling the nanowires with microcantilever resonators, enabling high-precision control of larger flows, and by using the nanowires as resonators themselves, allowing extremely small liquid volume handling. Both implementations are demonstrated by characterizing voltage-driven flow of ionic liquids along the surface of the nanowires. We find a voltage range where mass flow rate follows a nonlinear monotonic increase, establishing a steady flow regime for which we show mass flow control at rates from below 1 ag/s to above 100 fg/s and precise liquid handling down to the zeptoliter scale. The observed behavior of mass flow rate is consistent with a voltage-induced transition from static wetting to dynamic spreading as the mechanism underlying liquid transport along the nanowires.

Indexed as

ionic liquidsnanoelectromechanical systems (NEMS)nanofluidicsnanomechanical resonatorsopen fluidicssemiconductor nanowiressilicon nanowires

Identifiers

PMID37903505
PMCPMC10655260
OpenAlexW4388015755

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.