Evidence map›Paper›PMID 37903258›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2023

Human proteins curing yeast prions.

Songsong Wu, Herman K Edskes, Reed B Wickner

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.9field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

  1. Yeast as a Model for Human Disease.International journal of molecular sciences · 2026
    Review
  2. Article
  3. Article
  4. Yeast Prions: Discovery, Nature, Cellular Manipulation and Implication.Journal of microbiology and biotechnology · 2025
    Review
  5. Anti-Prion Systems in Saccharomyces cerevisiae.Journal of neurochemistry · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Songsong WuLaboratory of Biochemistry and Genetics, National Institute of Diabetes and Digestive and Kidney Diseases, NIH, Bethesda, MD 20892-0830.ORCID 0009-0004-6083-4821
Herman K EdskesLaboratory of Biochemistry and Genetics, National Institute of Diabetes and Digestive and Kidney Diseases, NIH, Bethesda, MD 20892-0830.ORCID 0000-0002-2708-2961
Reed B WicknerLaboratory of Biochemistry and Genetics, National Institute of Diabetes and Digestive and Kidney Diseases, NIH, Bethesda, MD 20892-0830.ORCID 0000-0003-0273-8247
National Institute of Diabetes and Digestive and Kidney Diseases · US

Funding

Prions of Yeast and Anti-Prion SystemsZIADK024950 · NIDDK · NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES · PI WICKNER, REED B. · 2009 to 2025
$25.2M
Intramural NIH HHS ZIA DK024950
6 · The paper itself

Abstract

Recognition that common human amyloidoses are prion diseases makes the use of the

Indexed as

PrionsSaccharomyces cerevisiae ProteinsAmyloidAnimalsDNA Repair EnzymesFungal ProteinsGlutathione PeroxidaseHSP70 Heat-Shock ProteinsHumansMammalsMutationNuclear ProteinsRNA Splicing FactorsSaccharomyces cerevisiaeAmyloidDNA Repair EnzymesFungal ProteinsGlutathione PeroxidaseHSP70 Heat-Shock ProteinsNuclear ProteinsPrionsPRPF19 protein, humanRNA Splicing FactorsSaccharomyces cerevisiae ProteinsamyloidBag5DNAJA1PRPF19URE3

Identifiers

PMID37903258
PMCPMC10636303
OpenAlexW4388033525

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.