ArticleProceedings of the National Academy of Sciences of the United States of America2023
Aberrant DJ-1 expression underlies L-type calcium channel hypoactivity in dendrites in tuberous sclerosis complex and Alzheimer's disease.
Open access · hybridAbstract read
In one paragraph
Article in Proceedings of the National Academy of Sciences of the United States of America, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.3field-weighted citation impact, top 11% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
9 citing papers in PubMed, 14 citations in OpenAlex.
- A commercially available DJ-1 antibody does not detectmicroPublication biology · 2026Article
- MicroRNA-mediated metabolic disruption as an emerging driver of alcohol use disorder.Nature communications · 2025Article
- 17β-estradiol status alters NMDAR function and antipsychotic-like activity in female rats.Molecular psychiatry · 2025Article
- Paradoxical mTORC1-Dependent microRNA-mediated Translation Repression in the Nucleus Accumbens of Male Mice Consuming Alcohol Attenuates Glycolysis.Nature communications · 2025Article
- Construction destruction: Contribution of dyregulated proteostasis to neurodevelopmental disorders.Current opinion in neurobiology · 2025Review
- DJ-1-mediated repression of the RNA-binding protein FMRP is predicted to impact known Alzheimer's disease-related protein networks.Journal of Alzheimer's disease : JAD · 2024Article
- Therapeutic Approaches to Tuberous Sclerosis Complex: From Available Therapies to Promising Drug Targets.Biomolecules · 2024Review
- Mitochondrial Structure and Function in Human Heart Failure.Circulation research · 2024Review
- Potential roles of voltage-gated ion channel disruption in Tuberous Sclerosis Complex.Frontiers in molecular neuroscience · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
18 authors at 3 institutions in 1 country.
Farr Niere *Department of Physiology and Pharmacology, Wake Forest University School of Medicine, Winston-Salem, NC 27157.ORCID 0000-0003-0287-0889
Ayse Uneri *Department of Physiology and Pharmacology, Wake Forest University School of Medicine, Winston-Salem, NC 27157.ORCID 0000-0002-9303-8184
Colin J McArdleDepartment of Physiology and Pharmacology, Wake Forest University School of Medicine, Winston-Salem, NC 27157.
Zhiyong DengDepartment of Physiology and Pharmacology, Wake Forest University School of Medicine, Winston-Salem, NC 27157.
Hailey X Egido-BetancourtDepartment of Physiology and Pharmacology, Wake Forest University School of Medicine, Winston-Salem, NC 27157.ORCID 0000-0002-6579-2411
Luisa P CacheauxDepartment of Physiology and Pharmacology, Wake Forest University School of Medicine, Winston-Salem, NC 27157.ORCID 0000-0001-7428-3355
Sanjeev V NamjoshiDepartment of Physiology and Pharmacology, Wake Forest University School of Medicine, Winston-Salem, NC 27157.
William C TaylorDepartment of Physiology and Pharmacology, Wake Forest University School of Medicine, Winston-Salem, NC 27157.
Xin WangDepartment of Internal Medicine, Gerontology and Geriatric Medicine, Wake Forest University School of Medicine, Winston-Salem, NC 27157.ORCID 0000-0002-2184-3328
Samuel H BarthDepartment of Physiology and Pharmacology, Wake Forest University School of Medicine, Winston-Salem, NC 27157.
Cameron ReynoldsonDepartment of Physiology and Pharmacology, Wake Forest University School of Medicine, Winston-Salem, NC 27157.
Juan PenarandaDepartment of Physiology and Pharmacology, Wake Forest University School of Medicine, Winston-Salem, NC 27157.
Michael P StiererDepartment of Physiology and Pharmacology, Wake Forest University School of Medicine, Winston-Salem, NC 27157.
Chelcie F HeaneyDepartment of Physiology and Pharmacology, Wake Forest University School of Medicine, Winston-Salem, NC 27157.ORCID 0000-0001-7712-1052
Suzanne CraftDepartment of Internal Medicine, Gerontology and Geriatric Medicine, Wake Forest University School of Medicine, Winston-Salem, NC 27157.
C Dirk KeeneDepartment of Laboratory Medicine and Pathology, University of Washington, Seattle, WA 98104.ORCID 0000-0002-5291-1469
Tao MaDepartment of Physiology and Pharmacology, Wake Forest University School of Medicine, Winston-Salem, NC 27157.ORCID 0000-0002-0763-7261
Kimberly F Raab-GrahamDepartment of Physiology and Pharmacology, Wake Forest University School of Medicine, Winston-Salem, NC 27157.ORCID 0000-0001-6502-057X
Wake Forest University · USNorth Carolina Agricultural and Technical State University · USUniversity of Washington · US
Funding
Translational pharmacoepidemiology: neuroprotection and neurotoxicity of antihypertensives and strong anticholinergicsU19AG066567 · NIA · KAISER FOUNDATION RESEARCH INSTITUTE · PI Christine L MacDonald · 2021 to 2026
$80.4MUniversity of Washington Alzheimer's Disease Research CenterP30AG066509 · NIA · UNIVERSITY OF WASHINGTON · PI Thomas J. Grabowski · 2020 to 2026
$29.0MWake Forest University School of Medicine Alzheimer's Disease Research CenterP30AG072947 · NIA · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI SUZANNE CRAFT · 2021 to 2026
$24.3MWake Forest Alzheimer's Disease Core CenterP30AG049638 · NIA · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI WHITLOW, CHRISTOPHER T · 2016 to 2020
$12.2MMULTI-DISCIPLINARY TRAINING IN THE BIOLOGY OF ALCOHOLISMT32AA007565 · NIAAA · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI BRIAN A MCCOOL · 1994 to 2026
$10.1MIsoform-specific roles of AMPK in synaptic failure and memory deficit in Alzheimer's DiseaseR01AG055581 · NIA · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI MA, TAO · 2017 to 2021
$2.9MRole of protein synthesis in Alzheimers disease-associated impairments of synaptic plasticity and memoryR01AG056622 · NIA · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI MA, TAO · 2017 to 2021
$2.4MTargeting protein synthesis dysregulation in Down syndrome-associated cognitive impairment with agingR01AG073823 · NIA · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI Tao Ma · 2021 to 2026
$2.3MNeural Substrates of Comorbid Alcohol Use Disorder and Post-Traumatic Stress DisorderR01AA026551 · NIAAA · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI WEINER, JEFFREY L. · 2017 to 2021
$1.9MMolecular Mechanism of Hippocampal network excitability in a novel, in vivo model of Tuberous Sclerosis ComplexR01NS105005 · NINDS · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI RAAB-GRAHAM, KIMBERLY FRANCES · 2018 to 2022
$1.9MThe Neurobiology of Drug AbuseT32DA041349 · NIDA · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI SARA RAULERSON JONES · 2017 to 2026
$1.8MBiochemical Studies Underlying Acute Ethanol's Antidepressant-like effects during Withdrawal in a Preclinical Model of Ethanol DependenceR01AA029691 · NIAAA · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI Kimberly Frances Raab-Graham · 2023 to 2026
$1.4MNIAAA NIH HHS R01 AA026551NIAAA NIH HHS R01 AA029691NIAAA NIH HHS T32 AA007565NIA NIH HHS P30 AG049638NIA NIH HHS P30 AG066509NIA NIH HHS P30 AG072947NIA NIH HHS R01 AG055581NIA NIH HHS R01 AG056622NIA NIH HHS R01 AG073823NIA NIH HHS R21 AG077271NIA NIH HHS U19 AG066567NIDA NIH HHS T32 DA041349NINDS NIH HHS F31 NS117096NINDS NIH HHS R01 NS105005NINDS NIH HHS R16 NS134542
Abstract
L-type voltage-gated calcium (Ca
Indexed as
Alzheimer DiseaseTuberous SclerosisAnimalsCalciumCalcium Channels, L-TypeDendritesMammalsMiceProtein Deglycase DJ-1CalciumCalcium Channels, L-TypePARK7 protein, mouseProtein Deglycase DJ-1Alzheimer’s diseasemammalian target of rapamycinRNA-binding proteintuberous sclerosis complexvoltage-gated calcium channels
Identifiers
What OpenQuestion holds
Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.