ArticleProceedings of the National Academy of Sciences of the United States of America2023
Agricultural intensification and childhood cancer in Brazil.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed, 34 citations in OpenAlex.
- Biopesticides vs conventional synthetic pesticides: A multidimensional evaluation of impacts on agricultural productivity and environmental health.Eco-Environment & Health · 2026Review
- Genetically Modified Plants in Agriculture.Biology · 2026Review
- Emerging risk identification in the food chain using text mining-supported monitoring of food safety news: insights from 2022 to 2023.Scientific reports · 2026Article
- Evaluating DNA damage in a South American marsupial through exfoliated cells of the buccal mucosa.Environmental science and pollution research international · 2026Article
- Article
- First trimester urine glyphosate concentrations and gestational diabetes in nulliparas: a nested case-control study.Environmental health : a global access science source · 2025Article
- Carcinogenic effects of long-term exposure from prenatal life to glyphosate and glyphosate-based herbicides in Sprague-Dawley rats.Environmental health : a global access science source · 2025Article
- Glyphosate exposure and GM seed rollout unequally reduced perinatal health.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Mercury Contamination and Co-exposures in the Amazon Basin: At the Center of the Planetary Environmental Crisis.Annals of global health · 2025Review
- Evidence concerning parental exposure to pesticides and the occurrence of leukemia in offspring: a systematic review.Frontiers in pediatrics · 2025Review
- Optimized Polymeric Membranes for Water Treatment: Fabrication, Morphology, and Performance.Polymers · 2024Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Over the last several decades, Brazil has become both the world's leading soy producer and the world's leading consumer of hazardous pesticides. Despite identified links between pesticide exposure and carcinogenesis, there has been little population-level research on the effects of pesticide intensification on broader human health in Brazil. We estimate the relationship between expanded soy production-and related community exposure to pesticides-on childhood cancer incidence using 15 y of data on disease mortality. We find a statistically significant increase in pediatric leukemia following expanded local soy production, but timely access to treatment mitigates this relationship. We show that pesticide exposure likely occurs via water supply penetration. Our findings represent only the tip of the iceberg for substantial health externalities of high-input crop production and land use change. Our results are of particular interest in developing contexts with demand for intensified food production systems and underscore the need for stronger regulation of pesticides and increased public health attention to exposure in the broader community.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.