ArticleHead and neck pathology2023
Clinicopathological Features of Metastasis to the Oral and Maxillofacial Region-Multicenter Study.
Article in Head and neck pathology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed, 5 citations in OpenAlex.
- Metastatic Cancers to the Oral Cavity: A 42-Year Experience.Head and neck pathology · 2026Article
- Oral metastasis of primary testicular choriocarcinoma: A case report and brief review of the literature.Journal of clinical and experimental dentistry · 2025Review
- Treatment strategy for maxillary gingival metastasis arising from gastric adenocarcinoma: A case report and literature review.Molecular and clinical oncology · 2025Article
- Case report: Tongue metastasis as an initial sign of clear cell renal cell carcinoma and its prognosis.Frontiers in oncology · 2024Article
- Renal clear cell carcinoma with bilateral parotid and orbital metastases - case report.Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologieArticle
Corrections and comments
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Authors and funding
33 authors at 12 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThis study aimed to investigate the clinicopathological features of metastases in the oral and maxillofacial regions.
methodsIn this retrospective study, biopsy records were obtained from referral centers for oral and maxillofacial diagnosis in Brazil, Guatemala, Mexico, and South Africa.
resultsA total of 120 cases were evaluated. Of these, 53.78% affected female patients, with a mean age of 57.64 years. Intraosseous lesions were more frequent, particularly in the posterior region of the mandible (49.58%). Clinically, most cases presented with symptomatic swelling, with an average evolution time of 25 months. The clinical diagnostic hypothesis in most instances was that of a malignant lesion. Breast cancer was the most common primary tumor location in females, while lung origin was most common in males. In most cases, the primary cancer was an adenocarcinoma (44.73%). The follow-up period was available for 29 cases, and out of these, 20 had died due to the disease.
conclusionAlthough this is a rare condition, clinicians should be aware that any oral lesions have the possibility of being metastatic, particularly in individuals with a previous history of cancer. The findings from this study could assist clinicians in prompt diagnosing these lesions and subsequent conducting oncologic assessments and treatment.
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