Evidence map›Paper›PMID 37902819›Full record

ArticleJMIR research protocols2023

A Multisite Electronic Health Record Integrated Remote Monitoring Intervention for Hypertension Improvement: Protocol for a Randomized Pragmatic Comparative Effectiveness Trial.

David R Lee, Matthew Chenoweth, Linh H Chuong, Chad W Villaflores, Miguel Cuevas, Sitaram Vangala, Jeff Borenstein, Hannah Kwak, Chidinma Chima-Melton, Maria Han and 14 more

Registry-linked trialOpen access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in JMIR research protocols, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05390502 (Evaluation of a University of California-wide Quality Improvement Effort to Improve Blood Pressure Control Using Remote), which is not on this map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 80% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05390502 naunknown statusnot on this map

Evaluation of a University of California-wide Quality Improvement Effort to Improve Blood Pressure Control Using Remote (Home) Monitoring

TypeinterventionalSponsorUniversity of California, Los AngelesRan2023 to 2024Enrolled660ConditionsHypertensionArmsmanual monitoring and general education on use, integrated monitoring and local wrap-around hypertension program
3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

24 authors at 4 institutions in 1 country.

David R Lee *Division of Geriatrics, University of California, Los Angeles, Los Angeles, CA, United States.ORCID https://orcid.org/0000-0003-2052-6192
Matthew Chenoweth *Fielding School of Public Health, University of California, Los Angeles, Los Angeles, CA, United States.ORCID https://orcid.org/0000-0002-5614-9803
Linh H Chuong *Fielding School of Public Health, University of California, Los Angeles, Los Angeles, CA, United States.ORCID https://orcid.org/0000-0002-0069-9611
Chad W Villaflores *Department of Medicine, University of California, Los Angeles, Los Angeles, CA, United States.ORCID https://orcid.org/0000-0003-1367-0882
Miguel Cuevas *Fielding School of Public Health, University of California, Los Angeles, Los Angeles, CA, United States.ORCID https://orcid.org/0000-0003-4040-1434
Sitaram Vangala *Department of Medicine, University of California, Los Angeles, Los Angeles, CA, United States.ORCID https://orcid.org/0000-0002-8842-5702
Jeff BorensteinDepartment of Medicine, University of California, Los Angeles, Los Angeles, CA, United States.ORCID https://orcid.org/0009-0000-0213-940X
Hannah Kwak *Department of Medicine, University of California, Los Angeles, Los Angeles, CA, United States.ORCID https://orcid.org/0009-0004-8509-046X
Chidinma Chima-Melton *Division of Pulmonary and Critical Care Medicine, University of California, Los Angeles, Los Angeles, CA, United States.ORCID https://orcid.org/0000-0003-0730-9871
Maria Han *Department of Medicine, University of California, Los Angeles, Los Angeles, CA, United States.ORCID https://orcid.org/0000-0003-4516-7894
Samuel A Skootsky *Department of Medicine, University of California, Los Angeles, Los Angeles, CA, United States.ORCID https://orcid.org/0000-0002-9995-436X
Therese Chan Tack *Division of General Internal Medicine, University of California, San Francisco, San Francisco, CA, United States.ORCID https://orcid.org/0009-0001-4065-8929
Linda Branagan *Telehealth Resource Center, University of California, San Francisco, San Francisco, CA, United States.ORCID https://orcid.org/0000-0002-8275-752X
Heather Martin *Department of Pharmacy, University of California Davis Health, Davis, CA, United States.ORCID https://orcid.org/0009-0004-6214-3821
Reshma Gupta *Department of Internal Medicine, University of California, Davis Health, Sacramento, CA, United States.ORCID https://orcid.org/0000-0002-2108-3007
Linda Phan *Department of Pharmacy, University of California Davis Health, Davis, CA, United States.ORCID https://orcid.org/0009-0005-7016-382X
Michael A Sanchez *University of California Office of the President, Oakland, CA, United States.ORCID https://orcid.org/0009-0004-2551-4494
Mina M Malaak *Ambulatory and Community Practices, University of California, Los Angeles, Los Angeles, CA, United States.ORCID https://orcid.org/0009-0003-3875-6188
Anna Dermenchyan *Department of Medicine, University of California, Los Angeles, Los Angeles, CA, United States.ORCID https://orcid.org/0000-0002-9381-442X
Kandyce N Pearson *Ambulatory and Community Practices, University of California, Los Angeles, Los Angeles, CA, United States.ORCID https://orcid.org/0009-0004-4219-5675
Marine Altunyan *Ambulatory and Community Practices, University of California, Los Angeles, Los Angeles, CA, United States.ORCID https://orcid.org/0009-0007-6954-7740
Peter F Barakat *Ambulatory and Community Practices, University of California, Los Angeles, Los Angeles, CA, United States.ORCID https://orcid.org/0009-0009-1421-0977
Ray Pablo *University of California Health Data Warehouse, University of California Health, Irvine, CA, United States.ORCID https://orcid.org/0000-0001-6861-5990
Catherine Sarkisian *Department of Medicine, University of California, Los Angeles, Los Angeles, CA, United States.ORCID https://orcid.org/0000-0003-2768-2323
University of California, Los Angeles · USUniversity of California, Davis · USUniversity of California, San Francisco · USExecutive Office of the President · US

Funding

UCLA Clinical Translational Science InstituteUL1TR001881 · NCATS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI ARLEEN F. BROWN, ARASH NAEIM · 2016 to 2026
$118.1M
Midcareer Award in Patient-Oriented Community-Academic Partnered Aging ResearchK24AG047899 · NIA · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI SARKISIAN, CATHERINE A · 2014 to 2025
$2.0M
NCATS NIH HHS UL1 TR001881NIA NIH HHS K24 AG047899
6 · The paper itself

Abstract

backgroundHypertension is a major contributor to various adverse health outcomes. Although previous studies have shown the benefits of home blood pressure (BP) monitoring over office-based measurements, there is limited evidence comparing the effectiveness of whether a BP monitor integrated into the electronic health record is superior to a nonintegrated BP monitor.

objectiveIn this paper, we describe the protocol for a pragmatic multisite implementation of a quality improvement initiative directly comparing integrated to nonintegrated BP monitors for hypertension improvement.

methodsWe will conduct a randomized, comparative effectiveness trial at 3 large academic health centers across California. The 3 sites will enroll a total of 660 participants (approximately n=220 per site), with 330 in the integrated BP monitor arm and 330 in the nonintegrated BP control arm. The primary outcome of this study will be the absolute difference in systolic BP in mm Hg from enrollment to 6 months. Secondary outcome measures include binary measures of hypertension (controlled vs uncontrolled), hypertension-related health complications, hospitalizations, and death. The list of possible participants will be generated from a central data warehouse. Randomization will occur after enrollment in the study. Participants will use their assigned BP monitor and join site-specific hypertension interventions. Cross-site learning will occur at regular all-site meetings facilitated by the University of California, Los Angeles Value-Based Care Research Consortium. A pre- and poststudy questionnaire will be conducted to further evaluate participants' perspectives regarding their BP monitor. Linear mixed effects models will be used to compare the primary outcome measure between study arms. Mixed effects logistic regression models will be used to compare secondary outcome measures between study arms.

resultsThe study will start enrolling participants in the second quarter of 2023 and will be completed by the first half of 2024. Results will be published by the end of 2024.

conclusionsThis pragmatic trial will contribute to the growing field of chronic care management using remote monitoring by answering whether a hypertension intervention coupled with an electronic health record integrated home BP monitor improves patients' hypertension better than a hypertension intervention with a nonintegrated BP monitor. The outcomes of this study may help health system decision makers determine whether to invest in integrated BP monitors for vulnerable patient populations.

trial registrationClinicalTrials.gov NCT05390502; clinicaltrials.gov/study/NCT05390502. INTERNATIONAL REGISTERED REPORT IDENTIFIER (IRRID): PRR1-10.2196/45915.

Indexed as

blood pressureEHRelectronic health recordhypertensionhypertensiveimprovement sciencemonitormonitoringrandomized controlled trialRCTremote blood pressure monitoring

Identifiers

PMID37902819
PMCPMC10644190
OpenAlexW4384835423

What OpenQuestion holds

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LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.