Evidence map›Paper›PMID 37902275›Full record

ArticleInternational journal of cancer2024

Prediagnostic serum concentrations of per- and polyfluoroalkyl substances and risk of papillary thyroid cancer in the Finnish Maternity Cohort.

Jessica M Madrigal, Rebecca Troisi, Heljä-Marja Surcel, Hanna Öhman, Juha Kivelä, Hannu Kiviranta, Panu Rantakokko, Jani Koponen, Danielle N Medgyesi, Cari M Kitahara and 5 more

Abstract read
In one paragraph

Article in International journal of cancer, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  14. Endocrine-disrupting chemicals and thyroid cancer.Turkish journal of medical sciences · 2025
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Jessica M MadrigalOccupational & Environmental Epidemiology Branch, Division of Cancer Epidemiology & Genetics (DCEG), National Cancer Institute (NCI), Rockville, Maryland, USA.ORCID 0000-0001-5303-5109
Rebecca TroisiTrans-Divisional Research Program, DCEG, NCI, Rockville, Maryland, USA.
Heljä-Marja SurcelBiobank Borealis of Northern Finland, Oulu University Hospital, Oulu, Finland.
Hanna ÖhmanBiobank Borealis of Northern Finland, Oulu University Hospital, Oulu, Finland.
Juha KiveläBiobank Borealis of Northern Finland, Oulu University Hospital, Oulu, Finland.
Hannu KivirantaFinnish Institute for Health and Welfare/Environmental Health Unit, Kuopio, Finland.
Panu RantakokkoFinnish Institute for Health and Welfare/Environmental Health Unit, Kuopio, Finland.
Jani KoponenFinnish Institute for Health and Welfare/Environmental Health Unit, Kuopio, Finland.
Danielle N MedgyesiOccupational & Environmental Epidemiology Branch, Division of Cancer Epidemiology & Genetics (DCEG), National Cancer Institute (NCI), Rockville, Maryland, USA.ORCID 0000-0001-8825-5750
Cari M KitaharaRadiation Epidemiology Branch, DCEG, NCI, Rockville, Maryland, USA.ORCID 0000-0001-6416-4432
Katherine A McGlynnMetabolic Epidemiology Branch, DCEG, NCI, Rockville, Maryland, USA.ORCID 0000-0003-2329-9933
Joshua SampsonBiostatistics Branch, DCEG, NCI, Rockville, Maryland, USA.
Paul S AlbertBiostatistics Branch, DCEG, NCI, Rockville, Maryland, USA.
Mary H WardOccupational & Environmental Epidemiology Branch, Division of Cancer Epidemiology & Genetics (DCEG), National Cancer Institute (NCI), Rockville, Maryland, USA.
Rena R JonesOccupational & Environmental Epidemiology Branch, Division of Cancer Epidemiology & Genetics (DCEG), National Cancer Institute (NCI), Rockville, Maryland, USA.ORCID 0000-0003-1294-1679

Funding

Cancer Risk and Environmental ExposuresZIACP010125 · NCI · DIVISION OF CANCER EPIDEMIOLOGY AND GENETICS · PI PURDUE, MARK · 2009 to 2025
$41.3M
INVESTIGATIONS OF ENVIRONMENTAL EXPOSURES AND CANCERZ01CP010125 · NCI · DIVISION OF CANCER EPIDEMIOLOGY AND GENETICS · PI CANTOR, KENNETH · 1996 to 2008
$108k
Division of Cancer Epidemiology and Genetics, National Cancer Institute ZIA CP010125-28Intramural NIH HHS Z01 CP010125Intramural NIH HHS Z99 CA999999Intramural NIH HHS ZIA CP010125
6 · The paper itself

Abstract

Human exposure to per- and polyfluoroalkyl substances (PFAS) occurs globally through contaminated food, dust, and drinking water. Studies of PFAS and thyroid cancer have been limited. We conducted a nested case-control study of prediagnostic serum levels of 19 PFAS and papillary thyroid cancer (400 cases, 400 controls) in the Finnish Maternity Cohort (pregnancies 1986-2010; follow-up through 2016), individually matched on sample year and age. We used conditional logistic regression to estimate odds ratios (OR) and 95% confidence intervals (CI) for log

Indexed as

Alkanesulfonic AcidsEnvironmental PollutantsFluorocarbonsSulfonic AcidsThyroid NeoplasmsCase-Control StudiesFemaleFinlandHumansPregnancyThyroid Cancer, PapillaryAlkanesulfonic AcidsEnvironmental PollutantsFluorocarbonsperfluorohexanesulfonic acidperfluorooctaneperfluorooctane sulfonic acidSulfonic Acidsper- and polyfluoroalkyl substancespersistent pollutantsPFASPFOAPFOSthyroid cancer

Identifiers

PMID37902275
PMCPMC11286200

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.