ArticleFoot & ankle international2024
Nicotine Dependence and Rates of Postoperative Complications in Achilles Tendon Repair.
Article in Foot & ankle international, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
5 citing papers in PubMed, 9 citations in OpenAlex.
- Nontobacco Nicotine Dependence Is Associated with Increased Postoperative Complications Following Breast Reconstruction.Plastic and reconstructive surgery. Global open · 2026Article
- Effect of Comorbidities on Short-Term Postoperative Complications Following total Shoulder Arthroplasty: A TriNetX Study.Journal of the American Academy of Orthopaedic Surgeons. Global research & reviews · 2026Article
- Isolated Flexor Hallucis Longus Tendon Transfer for Chronic Achilles Tendon Rupture: Systematic Review and Meta-Analysis.Healthcare (Basel, Switzerland) · 2025Review
- Non-Tobacco Nicotine Use and Complications in Free Flap Repair in Head and Neck Cancer.The Laryngoscope · 2025Article
- Smokers present a three times higher risk of graft failure after ACL reconstruction: A single-centre retrospective analysis.Journal of experimental orthopaedics · 2025Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
backgroundNicotine is a modifiable risk factor that is well demonstrated to cause deleterious effects on tendon healing and overall health. Individuals that have a dependence on nicotine may be at an elevated risk for numerous postoperative complications when compared to nondependent patients. The purpose of this study is to evaluate the complications postoperatively between nicotine- and non-nicotine-dependent Achilles tendon repairs.
methodsThe global health network database, TriNetX, was used to access and analyze deidentified patient information. Two cohorts were identified for the purposes of this study. Cohort A was defined as patients who had an Achilles tendon repair (
resultsA total of 2117 nicotine-dependent patients were matched with 18 102 non-nicotine-dependent patients. After propensity matching for age at event, ethnicity, race, sex, and type 2 diabetes mellitus, nicotine-dependent patients who underwent Achilles tendon repair experienced higher associated risk for numerous postoperative complications. When compared to nondependent patients, nicotine-dependent patients had increased risk for wound disruption (risk ratio [RR] 1.55, 95% CI 1.11-2.16) and infection following a procedure (RR 1.64, 95% CI 1.09-2.47) within 90 days post Achilles tendon repair.
conclusionIn this database study using propensity matching, nicotine-dependent patients who underwent Achilles tendon repair were correlated with an increased associated risk for wound disruption and infection after a procedure than their non-nicotine-dependent counterpart. LEVEL OF EVIDENCE: Level III, retrospective cohort study.
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