Evidence map›Paper›PMID 37901227›Full record

ArticleFrontiers in immunology2023

Significance of HLA-E and its two NKG2 receptors in development of complications after allogeneic transplantation of hematopoietic stem cells.

Jagoda Siemaszko, Piotr Łacina, Donata Szymczak, Agnieszka Szeremet, Maciej Majcherek, Anna Czyż, Małgorzata Sobczyk-Kruszelnicka, Wojciech Fidyk, Iwona Solarska, Barbara Nasiłowska-Adamska and 7 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.0field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 7 institutions in 1 country.

Jagoda SiemaszkoLaboratory of Clinical Immunogenetics and Pharmacogenetics, Hirszfeld Institute of Immunology and Experimental Therapy, Polish Academy of Sciences, Wroclaw, Poland.
Piotr ŁacinaLaboratory of Clinical Immunogenetics and Pharmacogenetics, Hirszfeld Institute of Immunology and Experimental Therapy, Polish Academy of Sciences, Wroclaw, Poland.
Donata SzymczakDepartment of Hematology, Blood Neoplasms and Bone Marrow Transplantation, Wroclaw Medical University, Wroclaw, Poland.
Agnieszka SzeremetDepartment of Hematology, Blood Neoplasms and Bone Marrow Transplantation, Wroclaw Medical University, Wroclaw, Poland.
Maciej MajcherekDepartment of Hematology, Blood Neoplasms and Bone Marrow Transplantation, Wroclaw Medical University, Wroclaw, Poland.
Anna CzyżDepartment of Hematology, Blood Neoplasms and Bone Marrow Transplantation, Wroclaw Medical University, Wroclaw, Poland.
Małgorzata Sobczyk-KruszelnickaDepartment of Bone Marrow Transplantation and Hematology-Oncology, Maria Sklodowska-Curie Memorial Cancer Center and Institute of Oncology, Gliwice, Poland.
Wojciech FidykDepartment of Bone Marrow Transplantation and Hematology-Oncology, Maria Sklodowska-Curie Memorial Cancer Center and Institute of Oncology, Gliwice, Poland.
Iwona SolarskaInstitute of Hematology and Blood Transfusion Medicine, Warsaw, Poland.
Barbara Nasiłowska-AdamskaInstitute of Hematology and Blood Transfusion Medicine, Warsaw, Poland.
Patrycja SkowrońskaCell and Tissue Bank, University Medical Center in Gdansk, Gdansk, Poland.
Maria BieniaszewskaDepartment of Hematology and Transplantology, Medical University of Gdansk, Gdansk, Poland.
Agnieszka TomaszewskaDepartment of Hematology, Transplantation and Internal Medicine, Medical University of Warsaw, Warsaw, Poland.
Grzegorz W BasakDepartment of Hematology, Transplantation and Internal Medicine, Medical University of Warsaw, Warsaw, Poland.
Sebastian GiebelDepartment of Bone Marrow Transplantation and Hematology-Oncology, Maria Sklodowska-Curie Memorial Cancer Center and Institute of Oncology, Gliwice, Poland.
Tomasz WróbelDepartment of Hematology, Blood Neoplasms and Bone Marrow Transplantation, Wroclaw Medical University, Wroclaw, Poland.
Katarzyna Bogunia-KubikLaboratory of Clinical Immunogenetics and Pharmacogenetics, Hirszfeld Institute of Immunology and Experimental Therapy, Polish Academy of Sciences, Wroclaw, Poland.
Wroclaw Medical University · PLThe Maria Sklodowska-Curie National Research Institute of Oncology · PLGdańsk Medical University · PLInstytut Hematologii i Transfuzjologi · PLLudwik Hirszfeld Institute of Immunology and Experimental Therapy · PLMedical University of Warsaw · PLPolish Academy of Sciences · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Transplantation of hematopoietic stem cells (HSCT) is a procedure commonly used in treatment of various haematological disorders which is associated with significantly improved survival rates. However, one of its drawbacks is the possibility of development of post-transplant complications, including acute and chronic graft-versus-host disease (GvHD) or CMV infection. Various studies suggested that NK cells and their receptors may affect the transplant outcome. In the present study, patients and donors were found to significantly differ in the distribution of the

Indexed as

Cytomegalovirus InfectionsGraft vs Host DiseaseHematopoietic Stem Cell TransplantationHistocompatibility Antigens Class INK Cell Lectin-Like Receptor Subfamily CHematopoietic Stem CellsHLA-E AntigensHumansTransplantation, HomologousHistocompatibility Antigens Class IHLA-E AntigensKLRC1 protein, humanKLRC2 protein, humanNK Cell Lectin-Like Receptor Subfamily CHLA-EHSCTNK cell receptorsNK cellsNKG2ANKG2CsHLA-Etransplant outcome

Identifiers

PMID37901227
PMCPMC10611459
OpenAlexW4387603428

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.