Evidence map›Paper›PMID 37901201›Full record

ArticleTranslational animal science2023

Polyphenols as a partial replacement for vitamin E in nursery pig diets.

Zhong-Xing Rao, Mike D Tokach, Jason C Woodworth, Joel M DeRouchey, Robert D Goodband, Apoorva S Shah, Brandon H Foley, Karsten C Kjeldsen, Grete Brunsgaard, Jordan T Gebhardt

Open access · goldAbstract read
In one paragraph

Article in Translational animal science, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
0.6field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 3 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Influence of added 1,25(OH)Translational animal science · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 2 countries.

Zhong-Xing RaoDepartment of Animal Sciences and Industry, College of Agriculture, Kansas State University, Manhattan KS 66506, USA.
Mike D TokachDepartment of Animal Sciences and Industry, College of Agriculture, Kansas State University, Manhattan KS 66506, USA.
Jason C WoodworthDepartment of Animal Sciences and Industry, College of Agriculture, Kansas State University, Manhattan KS 66506, USA.ORCID https://orcid.org/0000-0001-7268-4278
Joel M DeRoucheyDepartment of Animal Sciences and Industry, College of Agriculture, Kansas State University, Manhattan KS 66506, USA.
Robert D GoodbandDepartment of Animal Sciences and Industry, College of Agriculture, Kansas State University, Manhattan KS 66506, USA.
Apoorva S ShahSAM Nutrition, Bloomington, MN 55435, USA.
Brandon H FoleySAM Nutrition, Bloomington, MN 55435, USA.
Karsten C KjeldsenR2 Agro, Hedensted, Denmark.
Grete BrunsgaardR2 Agro, Hedensted, Denmark.
Jordan T GebhardtDepartment of Diagnostic Medicine/Pathobiology, College of Veterinary Medicine, Kansas State University, Manhattan KS 66506, USA.ORCID https://orcid.org/0000-0002-6144-6714
Kansas State University · USAgro Business Park · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A total of 300 pigs (241 × 600; DNA, Columbus, NE; initially 6.0 ± 0.01 kg) were used in a 42-d trial to determine the effects of vitamin E levels and partially replacing vitamin E with a polyphenol (Cabanin CSD, R2 Argo, Denmark) on growth performance, complete blood count, serum thiobarbituric acid reactive substances (TBARS), superoxide dismutase (SOD), and cytokine panel. Sixty pens of pigs were weighed and allotted to one of the five dietary treatments in a completely randomized design with 12 pens per treatment. A control treatment was formulated to provide 15 IU/kg of vitamin E equivalence from vitamin E. This control treatment was then used as a base for three replacement strategy diets to determine the effects of replacing an additional 60 IU/kg of vitamin E with polyphenol in diets containing a basal level of vitamin E requirement estimate (15 IU/kg). First, an additional 60 IU/kg of vitamin E was added for a total of 75 IU/kg of vitamin E equivalence. Second, 50% of the additional vitamin E (30 IU/kg) was replaced with the equivalency of polyphenol. Third, all 60 IU/kg of the additional vitamin E was replaced with the equivalency of polyphenol. To evaluate whether there are negative effects of feeding nursery pigs a high level of polyphenol, a fifth treatment was formulated to provide 575 IU/kg of vitamin E equivalence with 75 IU/kg from vitamin E and 500 IU/kg from polyphenol. Whole blood and serum samples were collected on days 10 and 42, and pig weights and feed disappearance were measured on days 10, 21, 31, 38, and 42. For growth performance, increasing vitamin E equivalence tended to improve (quadratic,

Indexed as

antioxidantgrowthnursery pigpolyphenolvitamin E

Identifiers

PMID37901201
PMCPMC10601450
OpenAlexW4387312719

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.