Evidence map›Paper›PMID 37900972›Full record

ReviewBiomedicine hub

Population Genome Programs across the Middle East and North Africa: Successes, Challenges, and Future Directions.

Hagar Ateia, Pauline Ogrodzki, Hannah V Wilson, Subhashini Ganesan, Rabih Halwani, Ashish Koshy, Walid A Zaher

Abstract readReview
In one paragraph

Review in Biomedicine hub. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Biomolecules & biomedicine · 2026
    Pooled it
  2. Review
  3. Review
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Review
  10. Genomics in Health and Biomedicine.Advances in experimental medicine and biology · 2026
    Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. Article
  17. Review
  18. Review
  19. Article
  20. Cancer Genetics in the Arab World.Technology in cancer research & treatment
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Hagar AteiaG42 Healthcare, Masdar City Abu Dhabi, UAE.
Pauline OgrodzkiG42 Healthcare, Masdar City Abu Dhabi, UAE.
Hannah V WilsonIROS (Insights Research Organization and Solutions), Abu Dhabi, UAE.
Subhashini GanesanG42 Healthcare, Masdar City Abu Dhabi, UAE.
Rabih HalwaniSharjah University, Sharjah, UAE.
Ashish KoshyG42 Healthcare, Masdar City Abu Dhabi, UAE.
Walid A ZaherG42 Healthcare, Masdar City Abu Dhabi, UAE.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this review, we discuss the current state of population genome programs (PGPs) conducted in the Middle East and North African (MENA) region. This region has high prevalence of genetic diseases and significant health challenges as well as being a significantly underrepresented population in public genetic databases. The majority of ongoing PGPs represent regions in Europe, North and South America, South Asia, Australia, and Africa, with little to no descriptive information highlighted only on the MENA Region when it comes to genome programs databases, outcomes, or the challenges that MENA region countries may face establishing their own national programs. This review has identified 6 PGPs currently underway in the MENA region, namely in the Kingdom of Saudi Arabia, Qatar, Egypt, the United Arab Emirates, Bahrain, and Iran. Due to the rapidly growing involvement of the MENA region in national-scale genomic data collection, an increase in representation in public genetic databases is to be expected to occur in the near future. Whilst significant progress is being made in some MENA countries, future initiatives as well as ongoing programs will be facing several challenges related to collaboration, finance, infrastructure and institutional data access, data analysis, sustainability, health records, and biobanks. The review also reiterates the need for ensuring ethical and regulated genomic initiatives which can drive developments in personalized medicine treatments to improve patient prognosis and quality of life.

Indexed as

ChallengesMiddle eastPopulation genome programsPrecision medicineWhole-genome sequencing

Identifiers

PMID37900972
PMCPMC10601860

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.