Evidence map›Paper›PMID 37900909›Full record

ArticleComplex psychiatry

Sensitive Periods for the Effect of Child Maltreatment on Psychopathology Symptoms in Adolescence.

Erin C Dunn, Daniel S Busso, Kathryn A Davis, Andrew D A C Smith, Colter Mitchell, Henning Tiemeier, Ezra S Susser

Open access · greenAbstract read
In one paragraph

Article in Complex psychiatry. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
6.0field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 19 citations in OpenAlex.

  1. Differential effects of childhood maltreatment types and timing on psychopathology in formerly out-of-home placed young adults.European psychiatry : the journal of the Association of European Psychiatrists · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Erin C DunnCenter for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA.
Daniel S BussoCenter for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA.
Kathryn A DavisCenter for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA.
Andrew D A C SmithApplied Statistics Group, University of the West of England at Bristol, Bristol, UK.
Colter MitchellInstitute for Social Research, University of Michigan, Ann Arbor, MI, USA.
Henning TiemeierDepartment of Child Psychiatry, Erasmus Medical Center, Rotterdam, The Netherlands.
Ezra S SusserDepartment of Epidemiology, Mailman School of Public Health, Columbia University, New York, NY, USA.
Harvard University · USMassachusetts General Hospital · USColumbia University · USUniversity of Michigan–Ann Arbor · US

Funding

Fragile Families and the Transition to AdulthoodR01HD036916 · NICHD · PRINCETON UNIVERSITY · PI Kathryn Edin, Jane Waldfogel · 1999 to 2026
$46.3M
Childhood adversity, DNA methylation, and risk for depression: A longitudinal study of sensitive periods in developmentR01MH113930 · NIMH · PURDUE UNIVERSITY · PI Erin Cathleen Dunn · 2017 to 2026
$6.6M
Epigenetic Mediation of Adverse Social Context on Stress Response, Socioemotional Development, and Health in a Population-based Study of Minority and Low SES Children and AdolescentsR01MD011716 · NIMHD · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI MITCHELL, COLTER M.S. · 2017 to 2022
$4.6M
ECONOMIC STATUS, PUBLIC POLICY, AND CHILD NEGLECTR01HD039135 · NICHD · PRINCETON UNIVERSITY · PI PAXSON, CHRISTINA H · 2000 to 2004
$3.1M
Child Care and Parental Employment in Fragile FamiliesR01HD040421 · NICHD · COLUMBIA UNIVERSITY TEACHERS COLLEGE · PI BROOKS-GUNN, JEANNE · 2002 to 2006
$2.8M
Genes, early adversity, and sensitive periods in social-emotional developmentK01MH102403 · NIMH · MASSACHUSETTS GENERAL HOSPITAL · PI DUNN, ERIN CATHLEEN · 2014 to 2017
$710k
NICHD NIH HHS R01 HD036916NICHD NIH HHS R01 HD039135NICHD NIH HHS R01 HD040421NIMHD NIH HHS R01 MD011716NIMH NIH HHS K01 MH102403NIMH NIH HHS R01 MH113930
6 · The paper itself

Abstract

Introduction: Child maltreatment is among the strongest risk factors for mental disorders. However, little is known about whether there are ages when children may be especially vulnerable to its effects. We sought to identify potential sensitive periods when exposure to the 2 most common types of maltreatment (neglect and harsh physical discipline) had a particularly detrimental effect on youth mental health. Methods: Data came from the Future of Families and Child Wellbeing Study (FFCWS), a birth cohort oversampled from "fragile families" ( Results: We identified sensitive periods for harsh physical discipline, whereby psychopathology symptom scores were highest among girls exposed at age 9 years ( Conclusion: Child maltreatment may have differential effects based on the child's sex, type of exposure, and the age at which it occurs. These findings provide additional evidence for clinicians assessing the benefits and drawbacks of screening efforts and point toward possible mechanisms driving increased vulnerability to psychopathology.

Indexed as

Accumulation of riskMaltreatmentNeglectPsychopathologySensitive periods

Identifiers

PMID37900909
PMCPMC10601948
OpenAlexW4324028836

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.