Evidence map›Paper›PMID 37900899›Full record

ArticleBiotribology (Oxford)2023

Translational Characterization of Macrophage Responses to Stable and Non-Stable CoCrMo Wear and Corrosion Debris Generated In-Situ for Total Hip Replacement.

Kathrin Ebinger, Lauryn Samelko, Simona Radice, Nadim J Hallab, Markus A Wimmer

Open access · greenAbstract read
In one paragraph

Article in Biotribology (Oxford), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.6field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 2 countries.

Kathrin EbingerDepartment of Orthopedic Surgery, Rush University Medical Center, Chicago, IL 60612.
Lauryn SamelkoDepartment of Orthopedic Surgery, Rush University Medical Center, Chicago, IL 60612.
Simona RadiceDepartment of Orthopedic Surgery, Rush University Medical Center, Chicago, IL 60612.
Nadim J HallabDepartment of Orthopedic Surgery, Rush University Medical Center, Chicago, IL 60612.
Markus A WimmerDepartment of Orthopedic Surgery, Rush University Medical Center, Chicago, IL 60612.
Rush University Medical Center · US

Funding

Determination of excessive immune reactivity to real time implant debris generateR21EB024039 · NIBIB · RUSH UNIVERSITY MEDICAL CENTER · PI HALLAB, NADIM JAMES, WIMMER, MARKUS ANTON · 2017 to 2018
$432k
NIBIB NIH HHS R21 EB024039
6 · The paper itself

Abstract

Metal wear and corrosion debris remain a limiting factor for long-term durability of total hip replacement (THR). Common wear particle production techniques for research differ from the actual tribocorrosion processes at the implant site, potentially causing loss of valuable information. The aim of this study was to investigate reactions to freshly generated and time-stabilized particles and ions released from CoCrMo-alloy using a bio-tribometer, which mimics conditions of the periprosthetic environment. THP-1 macrophages were challenged with freshly produced or time-stabilized wear debris. Wear generation took place in a custom-built bio-tribometer inside a CO

Indexed as

cobalt-chromium alloymacrophagesmetal ionsTribocorrosionwear particles

Identifiers

PMID37900899
PMCPMC10611437
OpenAlexW4387165627

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.