Evidence map›Paper›PMID 37900722›Full record

ArticleFrontiers in dental medicine2021

Amelogenin Peptide-Chitosan Hydrogel for Biomimetic Enamel Regrowth.

Kaushik Mukherjee, Amrita Chakraborty, Garima Sandhu, Sohaib Naim, E Bauza Nowotny, Janet Moradian-Oldak

Open access · goldAbstract read
In one paragraph

Article in Frontiers in dental medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.8field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 19 citations in OpenAlex.

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  16. Uniaxial Hydroxyapatite Growth on a Self-Assembled Protein Scaffold.International journal of molecular sciences · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Kaushik MukherjeeCenter for Craniofacial Molecular Biology, Herman Ostrow School of Dentistry, University of Southern California, Los Angeles, CA, United States.
Amrita ChakrabortyCenter for Craniofacial Molecular Biology, Herman Ostrow School of Dentistry, University of Southern California, Los Angeles, CA, United States.
Garima SandhuCenter for Craniofacial Molecular Biology, Herman Ostrow School of Dentistry, University of Southern California, Los Angeles, CA, United States.
Sohaib NaimDepartment of Biomedical Engineering, Whiting School of Engineering, Johns Hopkins, Baltimore, MD, United States.
E Bauza NowotnyCenter for Craniofacial Molecular Biology, Herman Ostrow School of Dentistry, University of Southern California, Los Angeles, CA, United States.
Janet Moradian-OldakCenter for Craniofacial Molecular Biology, Herman Ostrow School of Dentistry, University of Southern California, Los Angeles, CA, United States.
University of Southern California · USJohns Hopkins University · US

Funding

MATRIX-BASED MINERAL (MBM) ENAMEL BIOMIMETICSR01DE013414 · NIDCR · UNIVERSITY OF SOUTHERN CALIFORNIA · PI Janet Oldak · 2001 to 2026
$8.6M
A Peptide-Based Biomineralization Strategy for Tooth RepairR01DE027632 · NIDCR · UNIVERSITY OF SOUTHERN CALIFORNIA · PI OLDAK, JANET · 2019 to 2022
$1.6M
Monetite-Apatite Phase Transformation for an Enamel-Like Restorative MaterialR21DE027529 · NIDCR · UNIVERSITY OF SOUTHERN CALIFORNIA · PI OLDAK, JANET · 2019 to 2020
$454k
MATRIX BASED MINERAL ENAMEL-BIOMIMETICSR56DE013414 · NIDCR · UNIVERSITY OF SOUTHERN CALIFORNIA · PI OLDAK, JANET · 2018 to 2018
$387k
NIDCR NIH HHS R01 DE013414NIDCR NIH HHS R01 DE027632NIDCR NIH HHS R21 DE027529NIDCR NIH HHS R56 DE013414
6 · The paper itself

Abstract

We designed synthetic peptides that have demonstrated an effective remineralization potential to restore incipient enamel decay. In order to develop a clinically viable approach we incorporated the amelogenin-derived peptides P26 and P32 into chitosan hydrogel and examined their efficacy in the remineralization of enamel. Peptides in chitosan exhibited increased stability

Indexed as

bioactive peptidecariesenamelhydroxyapatiteQLFremineralization

Identifiers

PMID37900722
PMCPMC10611442
OpenAlexW3170688508

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.