ReviewJournal of the anus, rectum and colon2023
Clinical Guidelines for Diagnosis and Management of Cowden Syndrome/PTEN Hamartoma Tumor Syndrome in Children and Adults-Secondary Publication.
Open access · goldAbstract readReview
In one paragraph
Review in Journal of the anus, rectum and colon, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 2 of them syntheses that pooled it.
0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 2 pooled it
5.2field-weighted citation impact, top 4% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
28 citing papers in PubMed, 2 syntheses or guidelines pooled it, 34 citations in OpenAlex.
- Japanese society for cancer of the colon and rectum (JSCCR) guidelines 2024 for the clinical practice of hereditary colorectal cancer.International journal of clinical oncology · 2026Guideline
- [Hereditary genetic testing and its application in the diagnosis, treatment, and prevention of breast cancer].Magyar onkologia · 2025Guideline
- PTEN negative adenocarcinoma developed in a gastric hamartoma polyp of a Cowden syndrome patient.Clinical journal of gastroenterology · 2026Article
- Cowden syndrome-like phenotype with lymphangioma circumscriptum and an APC variant of uncertain significance.JAAD case reports · 2026Article
- Clinical Impact of Germline Multigene Sequencing in Pediatric Cohorts with a Wide Spectrum of Neoplasms.International journal of molecular sciences · 2026Article
- ERN GENTURIS cancer surveillance guideline for individuals with PTEN hamartoma tumour syndrome (PHTS).European journal of human genetics : EJHG · 2026Article
- Hereditary Endometrial Cancer: Lynch Syndrome, Mismatch Repair Deficiency, and Emerging Genetic Predispositions-A Comprehensive Review with Clinical and Laboratory Guidelines.International journal of molecular sciences · 2026Review
- Genetic tumor syndromes in female cancer: insights into inherited cancer predisposition and clinical implications.Archives of gynecology and obstetrics · 2026Review
- Cowden Syndrome in Childhood: Gastrointestinal Involvement in a Multisystem Genetic Disorder-A Case Report.Reports (MDPI) · 2026Article
- Preoperative risk stratification for pathological upgrading in colorectal polyps using explainable machine learning: implications for screening optimization and resource allocation.Frontiers in public health · 2026Article
- Coexisting PTEN and SDHB Mutations in a Pediatric Patient with PTEN Hamartoma Tumor Syndrome: a case report.Frontiers in pediatrics · 2026Article
- Macrocephaly and Characteristic MRI Findings as Early Clues to a Hereditary Overgrowth Syndrome.Cureus · 2026Article
- Population Prevalence of the Major Thyroid Cancer-Associated Syndromes.The Journal of clinical endocrinology and metabolism · 2025Article
- The Role of Video Capsule Endoscopy in Hereditary Polyposis Syndromes: A Narrative Review.Diagnostics (Basel, Switzerland) · 2025Review
- Risk Assessment and Fertility Counseling for Hereditary Gynecological Cancer Syndromes.Cancer medicine · 2025Review
- Multi-modal Malignancies in Cowden Syndrome: Diagnostic Challenges in a Suspected Case From a Low-Resource Setting.Cureus · 2025Article
- PTEN defects in cancer, from gene to protein molecular causes and therapeutic targets.Discover oncology · 2025Review
- Atypical Manifestations of Cowden Syndrome in Pediatric Patients.Diagnostics (Basel, Switzerland) · 2025Article
- Update on Pediatric Surveillance Recommendations for PTEN Hamartoma Tumor Syndrome, DICER1-Related Tumor Predisposition, and Tuberous Sclerosis Complex.Clinical cancer research : an official journal of the American Association for Cancer Research · 2025Review
- Cobblestone appearance of oral mucosa: A diagnostic conundrum.SAGE open medical case reports · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
28 authors at 20 institutions in 2 countries.
Tetsuji TakayamaDepartment of Gastroenterology and Oncology, Tokushima University Graduate School of Biomedical Sciences, Tokushima, Japan.
Naoki MugurumaDepartment of Gastroenterology and Oncology, Tokushima University Graduate School of Biomedical Sciences, Tokushima, Japan.
Masahiro IgarashiDepartment of Lower GI Medicine, Cancer Institute Hospital of JFCR, Tokyo, Japan.
Shozo OhsumiDepartment of Breast Oncology, NHO Shikoku Cancer Center, Matsuyama, Japan.
Shiro OkaDepartment of Gastroenterology, Hiroshima University Hospital, Hiroshima, Japan.
Fumihiko KakutaDivision of General Pediatrics and Gastroenterology, Miyagi Children's Hospital, Sendai, Japan.
Yoshiaki KuboDepartment of Dermatology, Tokushima University Graduate School of Biomedical Sciences, Tokushima, Japan.
Hideki KumagaiDepartment of Pediatrics, Jichi Medical University, Shimotsuke, Japan.
Mika SasakiDepartment of Pediatrics, National Hospital Organization Morioka Medical Center, Morioka, Japan.
Tamotsu SugaiDepartment of Molecular Diagnostic Pathology, Iwate Medical University, Morioka, Japan.
Kokichi SuganoOncogene Res Unit, Cancer Prevention Unit Tochigi Cancer Center Research Institute, Cancer Prevention, Genetic Counseling Clinic, Genome Center, Tochigi Cancer Center, Utsunomiya, Japan.
Yuko TakedaFaculty of Nursing and Medical Care, Graduate School of Health Management, Keio University, Tokyo, Japan.
Hisashi DoyamaDepartment of Gastroenterology, Ishikawa Prefectural Central Hospital, Kanazawa, Japan.
Kouji BannoDepartment of Obstetrics and Gynecology, Keio University School of Medicine, Tokyo, Japan.
Suguru FukahoriDepartment of Pediatric Surgery, Kurume University School of Medicine, Kurume, Japan.
Yoichi FurukawaDivision of Clinical Genome Research, The Institute of Medical Science, The University of Tokyo, Tokyo, Japan.
Takahiro HorimatsuDepartment of Real World Data Research and Development, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Hideki IshikawaDepartment of Molecular-Targeting Prevention, Kyoto Prefectural University of Medicine, Kyoto, Japan.
Takeo IwamaDepartment of Digestive Tract and General Surgery, Saitama Medical Center, Saitama Medical University, Kawagoe, Japan.
Yasushi OkazakiIntractable Disease Research Center, Graduate School of Medicine, Juntendo University, Tokyo, Japan.
Yutaka SaitoEndoscopy Division, National Cancer Center Hospital, Tokyo, Japan.
Nariaki MatsuuraOsaka International Cancer Institute, Osaka, Japan.
Michihiro MutohDepartment of Molecular-Targeting Prevention, Kyoto Prefectural University of Medicine, Kyoto, Japan.
Naohiro TomitaCancer Treatment Center, Toyonaka Municipal Hospital, Toyonaka, Japan.
Takashi AkiyamaDepartment of Pediatric Surgery, Chuden Hospital, Hiroshima, Japan.
Toshiki YamamotoDivision of Gastroenterology and Hepatology, Department of Medicine, Nihon University School of Medicine, Tokyo, Japan.
Hideyuki IshidaDepartment of Digestive Tract and General Surgery, Saitama Medical Center, Saitama Medical University, Kawagoe, Japan.
Yoshiko NakayamaDepartment of Pediatrics, Shinshu University School of Medicine, Matsumoto, Japan.
Tokushima University · JPKeio University · JPChubu Electric Power (Japan) · JPHiroshima University Hospital · JPIshikawa Prefectural Central Hospital · JPIwate Medical University · JPJichi Medical University · JPJuntendo University · JPKurume University · JPKyoto Prefectural University of Medicine · JPKyoto University · JPMiyagi Children's Hospital · JPNational Cancer Center · USNational Hospital Organization · JPNihon University · JPOsaka Medical Center for Cancer and Cardiovascular Diseases · JPSaitama Medical University · JPSasaki Institute · JPShikoku Cancer Center · JPShinshu University · JP
Funding
No grant is acknowledged in the PubMed record.
Abstract
Cowden syndrome (CS)/
Indexed as
cancercolorectal polypCowden syndromePTEN hamartoma tumor syndrome
Identifiers
What OpenQuestion holds
Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.