ReviewFrontiers in neurology2023
Economic and social values in the brain: evidence from lesions to the human ventromedial prefrontal cortex.
Review in Frontiers in neurology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed, 14 citations in OpenAlex.
- Article
- Reward and Imitation in Social Conformity.Brain and behavior · 2026Article
- A causal role of the ventromedial prefrontal cortex in regulating anticipated regret and risk behaviors in trait anxiety.Psychological medicine · 2026Article
- Microstimulation of the human dopaminergic midbrain enhances outcome-related happiness and reduces loss seeking.bioRxiv : the preprint server for biology · 2026Article
- Neural Mechanisms of Reciprocity Availability and Expectancy Violation During Social Interaction.Brain sciences · 2026Article
- Exploring partially shared valuation-related neural responses between abstract desirability and food incentive evaluation.Frontiers in human neuroscience · 2026Article
- Dorsomedial and ventromedial prefrontal cortex lesions differentially impact social influence and temporal discounting.PLoS biology · 2025Article
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Authors and funding
3 authors at 3 institutions in 1 country.
Funding
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Abstract
Making good economic and social decisions is essential for individual and social welfare. Decades of research have provided compelling evidence that damage to the ventromedial prefrontal cortex (vmPFC) is associated with dramatic personality changes and impairments in economic and social decision-making. However, whether the vmPFC subserves a unified mechanism in the social and non-social domains remains unclear. When choosing between economic options, the vmPFC is thought to guide decision by encoding value signals that reflect the motivational relevance of the options on a common scale. A recent framework, the "extended common neural currency" hypothesis, suggests that the vmPFC may also assign values to social factors and principles, thereby guiding social decision-making. Although neural value signals have been observed in the vmPFC in both social and non-social studies, it is yet to be determined whether they have a causal influence on behavior or merely correlate with decision-making. In this review, we assess whether lesion studies of patients with vmPFC damage offer evidence for such a causal role of the vmPFC in shaping economic and social behavior.
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