ReviewCureus2023
A Comprehensive Review of the Generalized Anxiety Disorder.
Review in Cureus, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
24 citing papers in PubMed, 46 citations in OpenAlex.
- Effect of mindfulness stress reduction combined with cognitive behavioral therapy on perinatal anxiety disorder and maternal-infant bonding.World journal of psychiatry · 2025Trial
- Efficacy and Safety of Acupuncture for Anxiety Disorders in Adults: A Systematic Review and Meta-Analysis.Psychiatry investigation · 2026Article
- Article
- Sex Differences in the Interaction of Epigenetic Risk and Trajectories of Default Mode Limbic Network Integration Predicting Childhood Anxiety.Research square · 2026Article
- A Network Analysis of Panic Disorder, Agoraphobia, and Generalized Anxiety Disorder in 463 Patients From a Psychiatric Hospital.Brain and behavior · 2026Article
- The role of the duration of untreated illness (DUI) in generalized anxiety disorder: a cross-sectional, multicenter study.CNS spectrums · 2026Article
- Network analysis of anxiety, depression, stress, and sleep disturbances in healthcare workers.Frontiers in psychiatry · 2026Article
- Experimental Study on Anxiolytic and Antidepressant Effects of Zhi-Chi-Jie-Yu Granules in CUMS Mice and Prediction of Underlying Molecular Mechanisms.Neuropsychiatric disease and treatment · 2026Article
- Clinical advances and multifactorial pathophysiological mechanisms of neuropsychiatric comorbidity in systemic sclerosis.Frontiers in immunology · 2026Review
- Anxiety is associated with systemic pro-inflammatory profile and plasma lipid changes in Mexican young adults.Frontiers in cellular neuroscience · 2026Article
- Disease Awareness, Care-Seeking Behavior, and Symptom Burden Among Japanese Patients with Generalized Anxiety Disorder: Results from a Web-Based Questionnaire of Clinical Trial Participants.Neuropsychiatric disease and treatment · 2026Article
- Altered Bilateral Motor Cortex Excitability and Peripheral Glutamate/GABA Imbalance in Generalized Anxiety Disorder: A TMS Investigation.Psychology research and behavior management · 2026Article
- Childhood Obesity and Overweight Are Associated with Higher Risk of Depression and Anxiety: A Cross-Sectional Study in Children Aged 6-9 Years.Life (Basel, Switzerland) · 2025Article
- Stressor-evoked heart rate, perceived physiological arousal, and anxiety symptoms in young adults.Journal of affective disorders · 2025Article
- Scaling of Ventral Hippocampal Activity during Anxiety.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Article
- Understanding the complex network of anxiety, depression, sleep problems, and smartphone addiction among college art students using network analysis.Frontiers in psychiatry · 2025Article
- Article
- Clinical application of abdominal breathing training and evaluation of physical and mental benefits in anxiety patients.Frontiers in psychology · 2025Article
- An exploratory qualitative pilot study assessing treatment-seeking behavior for generalized anxiety symptoms among people living with HIV/AIDS in Tanzania.PLOS mental health · 2025Article
- Consequences of bathroom restriction on transgender individuals with gastrointestinal conditions in the United States.Nature reviews. Gastroenterology & hepatology · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Excessive, uncontrollable, and usually unjustified worry about certain things is a sign of the mental and behavioral disease known as generalized anxiety disorder (GAD). Genetic research suggests that numerous genes are likely implicated in the development of GAD, even if much is yet unclear about this. As a result, if someone in a family has GAD, there is a high likelihood that someone else will also suffer from the illness, as well as another anxiety disorder. Individuals with GAD are frequently overly bothered about workaday affairs like health, assets, demise, family, accord issues, or effort challenges. Worry frequently interferes with daily functioning. Excessive concern, restlessness, difficulty sleeping, tiredness, irritability, sweating, and trembling are a few symptoms that may be present. For a formal diagnosis of GAD, symptoms must be persistent for at least six months and consistent. Conversion in the amygdala's utilitarian congruence and how it processes fear and anxiety have been linked to generalized anxiety disorder. Neurotransmitters, and particularly the gamma-aminobutyric acid (GABA) variant, have long been known to cause GAD through dysregulating amygdala activity in the brain. Anxiety, concern, or physical symptoms must significantly hinder social, academic, or occupational functioning in order to qualify for a GAD diagnosis. The Diagnostic and Statistical Manual of Mental Disorders-V (DSM-V) provides explicit ethos to aid doctors in identifying this disorder. Psychological therapy based on cognitive behavioral therapy (CBT) principles is effective in reducing anxiety symptoms for short-term treatment of GAD. In this, the patient's thinking ability and methods are focused. The main principle behind CBT is that your thought patterns affect your feelings, which in turn can affect your behavior. Drugs like antidepressants, buspirone, benzodiazepines, and can all be worn to goody GAD. Outside of therapy, patients with anxiety can learn to manage it by practicing relaxation methods, reframing unfavorable ideas, and adopting stress-relieving adjustments. Being socially active and setting aside time for proper self-care are crucial components of managing generalized anxiety disorder.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.