Evidence map›Paper›PMID 37900508›Full record

ArticleCureus2023

The Role of Sodium Oxybate in Idiopathic Hypersomnia: A Case Report Showing Improvement of Excessive Daytime Sleepiness and Reduced Symptoms.

Michael Vera Ricaurte, Jamshaid Akhtar, Palak Patel, Akshay Sundaram, Kirti K Kharel, Mohammad Kagzi

Open access · diamondAbstract readCase Reports
In one paragraph

Article in Cureus, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
0.2field-weighted citation impact, top 50% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it, 1 citations in OpenAlex.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 4 countries.

Michael Vera RicaurteGeneral Medicine, Universidad Central de Venezuela, Caracas, VEN.
Jamshaid AkhtarInternal Medicine, Midwest Sleep and Wellness Clinic, Chicago, USA.
Palak PatelInternal Medicine, Sir Sayajirao General (SSG) Hospital, Vadodara, IND.
Akshay SundaramInternal Medicine, Kasturba Medical College, Manipal, IND.
Kirti K KharelInternal Medicine, Nobel Medical College Teaching Hospital, Biratnagar, NPL.
Mohammad KagziSleep Medicine, Advocate Condell Medical Center, Chicago, USA.
Advocate Illinois Masonic Medical Center · USMidwest Orthopaedic Research Foundation · USCentral University of Venezuela · VE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Our aim is to report the clinical profile and outcome of patients diagnosed with idiopathic hypersomnia (IH). Idiopathic hypersomnolence is a complex, debilitating, and uncommon sleep disorder manifested mainly by chronic excessive daytime sleepiness (EDS). This paper reports on the treatment of a patient with idiopathic hypersomnia who was treated with low sodium oxybate (LXB) due to a lack of response to the first-line drug modafinil. This patient, who presented with worsening excessive daytime sleepiness, sleep drunkenness, and sleep disturbances, was diagnosed with idiopathic hypersomnia by overnight polysomnography (PSG) and a multiple sleep latency test (MSLT). Stimulant agent modafinil was prescribed along with sleep hygiene education. Her symptoms did not respond to modafinil, and she was switched to a recently approved newer medication, i.e., low sodium oxybate.

Indexed as

epworth sleepiness scaleidiopathic hypersomniamodafinilmultiple sleep latency testsodium oxybate

Identifiers

PMID37900508
PMCPMC10600639
OpenAlexW4387054405

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.