Evidence map›Paper›PMID 37900417›Full record

ReviewCureus2023

The Relationship Between Myocardial Infarction and Estrogen Use: A Literature Review.

Ayesha Javed, Phanish C Ravi, Sarah Bilal Delvi, Iqra Faraz Hussain, Arnaldo J Acosta G, Warda Iqbal, Vamsi Krishnamaneni, Saya Alasaadi, Swetapadma Pradhan, Rishabh Vashisht and 1 more

Open access · diamondAbstract readReview
In one paragraph

Review in Cureus, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 10 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 7 institutions in 5 countries.

Ayesha JavedGynecology, Heart's International Hospital, Rawalpindi, PAK.
Phanish C RaviMedicine and Surgery, Sri Venkata Sai Medical College, Telangana, IND.
Sarah Bilal DelviInternal Medicine, Vydehi Institute of Medical Sciences and Research Centre, Bangalore, IND.
Iqra Faraz HussainGynecology, Karachi Medical and Dental College, Karachi, PAK.
Arnaldo J Acosta GEndocrinology, Alfredo Van Grieken University Hospital, Coro, VEN.
Warda IqbalGynecology, Karachi Medical and Dental College, Karachi, PAK.
Vamsi KrishnamaneniInternal Medicine, Katuri Medical College and Hospital, Guntur, IND.
Saya AlasaadiMedicine, University College Dublin, Dublin, IRL.
Swetapadma PradhanMedicine, European University Faculty of Medicine, Tbilisi, GEO.
Rishabh VashishtInternal Medicine, Non Resident Indian (NRI) Medical College, Vijayawada, IND.
Shivani ModiInternal Medicine, Albert Einstein Healthcare Network, Philadelphia, USA.
Indian Medical Association · INEinstein Healthcare Network · USBenazir Bhutto Hospital · PKCork University Hospital · IEKarachi Medical and Dental College · PKSri Venkateswara Medical College and Ruia Hospital · INUniversity College Dublin · IE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This thorough literature evaluation was prompted by significant research into the complex interactions between estrogen use and myocardial infarction (MI). Estrogen has fascinated researchers because of its possible cardioprotective benefits and its impact on cardiovascular health. In order to clarify the connection between estrogen use and the risk of MI, this review critically examines the body of prior evidence. This review focuses on estrogen and its pivotal role in cardiovascular health, concentrating on lipid metabolism, vasodilation, inflammation, and endothelial function. It examines contentious data about estrogen therapy's heart-protective effects, taking into account age, initiation timing, dosage, and dosage of administration. Genetic and epigenetic influences on MI risk among estrogen users highlight intricate, personalized estrogen effects. The conclusion summarizes the main findings and emphasizes the need for an all-encompassing strategy for initiating and managing estrogen medication. It is crucial to consider patient-specific traits and risk factors to successfully customize treatment regimens. This review sheds vital light on the potential directions for better cardiovascular treatment for postmenopausal women by shedding light on the complex link between estrogen use and myocardial infarction. The review also identifies research gaps and future objectives in this area, highlighting the demand for novel medicines and individualized strategies to improve cardiovascular outcomes.

Indexed as

cvdestradiolestronemyocardial infarctiontransdermal estrogen

Identifiers

PMID37900417
PMCPMC10612533
OpenAlexW4387140939

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.