Evidence map›Paper›PMID 37900296›Full record

ArticleFrontiers in psychiatry2023

Hard-to-treat or hard-to-catch? Clinical features and therapeutic outcomes of help-seeking foster care youths with mood disorders.

Xavier Benarous, Hélène Lahaye, Hugues Pellerin, Angèle Consoli, David Cohen, Réal Labelle, Johanne Renaud, Priscille Gérardin, Fabienne El-Khoury, Judith van der Waerden and 1 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in psychiatry, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
1.3field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 5 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 6 institutions in 2 countries.

Xavier BenarousDepartment of Child and Adolescent Psychopathology, Amiens University Hospital, Amiens, France.
Hélène LahayeDepartment of Child and Adolescent Psychopathology, Amiens University Hospital, Amiens, France.
Hugues PellerinDepartment of Child and Adolescent Psychiatry, Pitié-Salpêtrière University Hospital, APHP, Paris, France.
Angèle ConsoliDepartment of Child and Adolescent Psychiatry, Pitié-Salpêtrière University Hospital, APHP, Paris, France.
David CohenDepartment of Child and Adolescent Psychiatry, Pitié-Salpêtrière University Hospital, APHP, Paris, France.
Réal LabelleDepartment of Psychology, Université du Québec à Montréal, Montréal, QC, Canada.
Johanne RenaudManulife Centre for Breakthroughs in Teen Depression and Suicide Prevention, Douglas Mental Health University Institute, McGill University, Montréal, QC, Canada.
Priscille GérardinDepartment of Child and Adolescent Psychopathology, Rouen University Hospital, Rouen, France.
Fabienne El-KhourySorbonne Université, INSERM, Institut Pierre Louis d'Epidémiologie et de Santé Publique, Equipe de Recherche en Epidémiologie Sociale, Paris, France.
Judith van der WaerdenSorbonne Université, INSERM, Institut Pierre Louis d'Epidémiologie et de Santé Publique, Equipe de Recherche en Epidémiologie Sociale, Paris, France.
Jean-Marc GuiléDepartment of Child and Adolescent Psychopathology, Amiens University Hospital, Amiens, France.
Inserm · FRSorbonne Université · FRCentre Hospitalier Universitaire de Rouen · FRCentre National de la Recherche Scientifique · FRDouglas Mental Health University Institute · CAUniversité du Québec à Montréal · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: The high level of emotional problems in youths placed in foster care contrasts with the limited use of evidence-based treatments. This study aims to better characterize the clinical features and therapeutic outcomes of foster care youths with mood disorders. Methods: A secondary analysis of data collected in the context of a French-Canadian clinical research network on pediatric mood disorders in four sites was conducted to compare three groups of patients with depressive or bipolar disorder: those without exposure to child welfare intervention (WCWI, Results: We observed a very high rate of academic problems in patients in the groups NPI/PI compared to those in the WCWI group. Patients in the PI group had more disruptive behavioral disorders (OR = 6.87, 95% CI [3.25-14.52]), trauma-related disorders (OR = 3.78, 95% CI [1.6-8.94]), and any neurodevelopmental disorders (OR = 2.73, 95% CI [1.36-5.49]) compared to the other groups (NPI/WCWI). Among inpatients, the Clinical Global Impression-Improvement scale and the change in the Children Global Assessment Scale during the hospital stay did not differ across the three groups. We observed a higher prescription rate of antipsychotics in the PI group compared to the NPI/WCWI groups, but no significant difference for antidepressants and mood stabilizers. Discussion: These findings support the view that, when provided with dedicated support, fostered inpatient youths can improve in a range comparable to other inpatients. Undetected neurodevelopmental disorders and academic problems are likely important contributors of the burden of mood disorders in these youths.

Indexed as

adverse chilhood experienceschild adversitycomplex psychotraumadepressive disorderdevelopmental psychotraumadisruptive mood dysregulation disorderearly-onset bipolar disorder

Identifiers

PMID37900296
PMCPMC10603296
OpenAlexW4387603385

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.