Evidence map›Paper›PMID 37900284›Full record

ArticleFrontiers in cell and developmental biology2023

Transcription and chromatin regulation by TAF4b during cellular quiescence of developing prospermatogonia.

Megan A Gura, Myles A Bartholomew, Kimberly M Abt, Soňa Relovská, Kimberly A Seymour, Richard N Freiman

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cell and developmental biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.3field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. The role(s) of NF-Y in development and differentiation.Cell death and differentiation · 2025
    Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Megan A Gura *MCB Graduate Program, Providence, RI, United States.
Myles A Bartholomew *MCB Graduate Program, Providence, RI, United States.
Kimberly M AbtMCB Graduate Program, Providence, RI, United States.
Soňa RelovskáDepartment of Molecular Biology, Cell Biology, and Biochemistry, Brown University, Providence, RI, United States.
Kimberly A SeymourDepartment of Molecular Biology, Cell Biology, and Biochemistry, Brown University, Providence, RI, United States.
Richard N FreimanMCB Graduate Program, Providence, RI, United States.
Brown University · USProvidence College · US

Funding

Tracking and Evaluation CoreU54GM115677 · NIGMS · BROWN UNIVERSITY · PI KOGUT, STEPHEN J · 2016 to 2025
$45.0M
Predoctoral Training in Molecular, Cellular, and Biochemical SciencesT32GM136566 · NIGMS · BROWN UNIVERSITY · PI Mark Aikens Johnson, Erica Nicole Larschan · 2020 to 2026
$3.1M
Dynamic Regulation of the Ovarian ReserveR01HD091848 · NICHD · BROWN UNIVERSITY · PI FREIMAN, RICHARD NEIL · 2018 to 2021
$1.7M
BD FACSAria Flow CytometerS10RR021051 · NCRR · BROWN UNIVERSITY · PI BROSSAY, LAURENT · 2007 to 2007
$403k
Fertility and TAF4b: Transcriptional Regulation of Murine Ovarian Reserve EstablishmentF31HD105340 · NICHD · BROWN UNIVERSITY · PI ABT, KIMBERLY M · 2021 to 2023
$140k
Unscrambling Eggs: TAF4B and Transcriptional Regulation of Meiosis I in Mouse OocytesF31HD097933 · NICHD · BROWN UNIVERSITY · PI GURA, MEGAN A · 2018 to 2021
$136k
NCRR NIH HHS S10 RR021051NICHD NIH HHS F31 HD097933NICHD NIH HHS F31 HD105340NICHD NIH HHS R01 HD091848NIGMS NIH HHS T32 GM136566NIGMS NIH HHS U54 GM115677
6 · The paper itself

Abstract

Prospermatogonia (ProSpg) link the embryonic development of male primordial germ cells to the healthy establishment of postnatal spermatogonia and spermatogonial stem cells. While these spermatogenic precursor cells undergo the characteristic transitions of cycling and quiescence, the transcriptional events underlying these developmental hallmarks remain unknown. Here, we investigated the expression and function of TBP-associated factor 4b (

Indexed as

male fertilityprospermatogoniaquiescencespermatogenesisspermatogonial stem cellsTAF4Btranscription

Identifiers

PMID37900284
PMCPMC10600471
OpenAlexW4387573785

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.