ArticleWorld journal of clinical cases2023
Correlation analysis of serum thyroglobulin, thyroid-stimulating hormone levels, and thyroid-cancer risk in thyroid nodule surgery.
Article in World journal of clinical cases, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed, 9 citations in OpenAlex.
- Preoperative diagnostic accuracy of thyroid follicular carcinoma using fluorine-18-fluorodeoxyglucose-positron emission tomography/computed tomography and blood data.Annals of nuclear medicine · 2026Article
- Behavior of serum thyroglobulin in relation to thyroid function under low-thyrotropin conditions in general practice.Frontiers in endocrinology · 2026Article
- Association of Anti-TPO Antibody and Inflammatory Markers with Thyroid Ultrasound FindingsEndocrine, metabolic & immune disorders drug targets · 2026Article
- The value of C-TIRADS combined with multidimensional indicators in the diagnosis of papillary thyroid carcinoma.Gland surgery · 2025Article
- A study on the correlation of thyroid nodules with METS-IR and SII in a population undergoing health checkups.Frontiers in endocrinology · 2025Article
- The impact of air pollutants on the risk of goiter based on a 9-year time series data.Frontiers in public health · 2025Article
- Effects ofAmerican journal of cancer research · 2025Article
- Advances in targeted therapy and biomarker research in thyroid cancer.Frontiers in endocrinology · 2024Review
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Authors and funding
4 authors at 1 institution in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
backgroundThyroglobulin (Tg) is one of the markers of thyroid cancer, and its concentration may be elevated in patients with malignant thyroid tumors. Thyroid-stimulating hormone (TSH) is secreted by the pituitary gland, which has a significant impact on thyroid gland function. Excessively high or low TSH levels may be associated with an increased risk of thyroid cancer. Thus, in-depth studies on the association of serum Tg and TSH levels with thyroid cancer risk in patients with thyroid nodules are warranted. This can help determine whether Tg and TSH levels can predict the degree of malignancy of thyroid nodules, which can in turn guide doctors in making accurate diagnoses and treatment decisions. Furthermore, such studies can provide more accurate diagnostic methods for thyroid nodules and help patients become aware of the presence of thyroid cancer as early as possible, thereby improving the success rate of treatment and prognosis.
aimTo investigate the association of serum Tg and TSH levels with the risk of thyroid cancer in patients undergoing thyroid nodule surgery.
methodsThe clinical data and laboratory examination results of 130 patients who underwent thyroid nodule surgery were retrospectively analyzed. Furthermore, their preoperative serum Tg and TSH levels were recorded. Histopathological examination conducted during follow-up revealed the presence of thyroid cancer. Correlation analysis were used to analyze the association of Tg and TSH levels with the risk of thyroid cancer.
resultsOf the 130 patients, 60 were diagnosed with thyroid cancer. Statistical analysis revealed a significant positive correlation between serum Tg levels and the risk of thyroid cancer (
conclusionIn patients who underwent thyroid nodule surgery, serum Tg levels exhibited a significant correlation with the risk of thyroid cancer but serum TSH levels did not. These findings suggest that serum Tg can serve as an important biomarker for assessing the risk of thyroid cancer in these patients.
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