Evidence map›Paper›PMID 37899966›Full record

ArticleIn silico pharmacology2023

A network pharmacology approach to explore pharmacological mechanisms of

Baldeep Kaur, Sandeep Kumar, Arvinder Kaur, Rajesh Kumar Goel

Abstract read
In one paragraph

Article in In silico pharmacology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Baldeep KaurDepartment of Pharmaceutical Sciences and Drug Research, Punjabi University, Patiala, Punjab 147002 India.
Sandeep KumarDepartment of Pharmacology, M. M. College of Pharmacy, M. M. (Deemed to be University), Mullana, Ambala, Haryana India.
Arvinder KaurDepartment of Pharmaceutical Sciences and Drug Research, Punjabi University, Patiala, Punjab 147002 India.
Rajesh Kumar GoelDepartment of Pharmaceutical Sciences and Drug Research, Punjabi University, Patiala, Punjab 147002 India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Network pharmacology approach has been observed a powerful tool to predict underlying complex pharmacological mechanism of herbs. Methodology: : Bioactive compounds of Results: The network analysis revealed that 5 targets (CASP3, TNF, VEGFA, PTGS2 and CNR1) might be the key therapeutic targets of asparagus on Epilepsy comorbid Alzheimer's disease. Based on high connectivity, four hub compounds with the highest connectivity were noted and it includes Shatavarin V, Sarsasapogenin, Shatavarin IX, and Shatavarin VI. A total of 19 KEGG terms were enriched as the potential pathways of Conclusion: This study envisaged the pharmacological and molecular mechanism of Supplementary Information: The online version contains supplementary material available at 10.1007/s40203-023-00169-x.

Indexed as

A. racemosus.Cognition impairmentEpilepsyNetwork pharmacology

Identifiers

PMID37899966
PMCPMC10611688

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.