Evidence map›Paper›PMID 37899804›Full record

ArticleSisli Etfal Hastanesi tip bulteni2023

Antibody Response to COVID-19 Vaccines in Healthcare Workers: Which One is More Successful? Homologous or Heterologous?

Zehra Cagla Karakoc, Didem Tascioglu, Bulent Ediz, Musa Caglan, Veysel Sabri Hancer, Tolga Simru Tugrul, Binnur Pinarbasi Simsek

Open access · hybridAbstract read
In one paragraph

Article in Sisli Etfal Hastanesi tip bulteni, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Zehra Cagla KarakocDepartment of Infectious Diseases and Clinical Microbiology, Istinye University, Faculty of Medicine, Istanbul, Türkiye.
Didem TasciogluDepartment of Infectious Diseases and Clinical Microbiology, Istinye University, Faculty of Medicine, Istanbul, Türkiye.
Bulent EdizDepartment of Biostatistics, Istinye University, Faculty of Medicine, Istanbul, Türkiye.
Musa CaglanDepartment of Chemisty, Bilecik Seyh Edebali University, Bilecik, Türkiye.
Veysel Sabri HancerDepartment of Medical Biology, Istinye University, Faculty of Medicine, Istanbul, Türkiye.
Tolga Simru TugrulDepartment of Anestesiology and Reanimation, Istinye University, Faculty of Medicine, Istanbul, Türkiye.
Binnur Pinarbasi SimsekDepartment of Gastroenterohepatology, Istinye University, Faculty of Medicine, Istanbul, Türkiye.
Istinye University · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: We aimed to determine the antibody levels created by COVID-19 vaccination in healthcare workers and the factors affecting the antibody response. Methods: Our research is a single-center, observational study that was prospectively designed and retrospectively analyzed at the beginning of the COVID-19 pandemic, and included 103 healthcare workers who received the three-dose regimen of COVID-19 vaccine. In accordance with the recommendations of the Ministry of Health of Turkey, the first two doses of CoronaVac vaccine were administered routinely, while the booster dose was given as BioNTech or CoronaVac (heterologous or homologous vaccination) depending on the preference of the volunteers. Antibody titers against the SARS-CoV-2 were measured in all individuals at different time points (1 month after the second dose of CoronaVac, before the booster dose [BioNTech or CoronaVac] at the fifth month and one month after the booster dose) with AESKULISA® SARS-CoV-2 S1 IgG (AESKU DIAGNOSTICS, Wendelsheim, Germany). Results: The mean age was 39.98±11.31 years, 62.1% of whom were women and 54.4% of them were accompanied by comorbid disease. After two doses of CoronaVac, the antibody titer averaged 49.50±33.15 U/mL in the 1 Conclusion: Our study, which reflects the data within the scope of the Turkey Ministry of Health's COVID-19 vaccination program determined that the antibody response after heterologous vaccination is better than in homologous vaccination. Antibody titer level in the 5

Indexed as

AntibodyCOVID-19health-care workersSARS-CoV-2vaccine

Identifiers

PMID37899804
PMCPMC10600628
OpenAlexW4323774918

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.