Evidence map›Paper›PMID 37899524›Full record

ArticleKorean journal of radiology2023

Bone Age Assessment Using Artificial Intelligence in Korean Pediatric Population: A Comparison of Deep-Learning Models Trained With Healthy Chronological and Greulich-Pyle Ages as Labels.

Pyeong Hwa Kim, Hee Mang Yoon, Jeong Rye Kim, Jae-Yeon Hwang, Jin-Ho Choi, Jisun Hwang, Jaewon Lee, Jinkyeong Sung, Kyu-Hwan Jung, Byeonguk Bae and 5 more

Open access · hybridAbstract read
In one paragraph

Article in Korean journal of radiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
39.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 25 citations in OpenAlex.

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  8. Automatic bone age assessment: a Turkish population study.Diagnostic and interventional radiology (Ankara, Turkey) · 2025
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

15 authors at 4 institutions in 1 country.

Pyeong Hwa KimDepartment of Radiology and Research Institute of Radiology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea.ORCID 0000-0003-4276-8803
Hee Mang YoonDepartment of Radiology and Research Institute of Radiology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea. espoirhm@gmail.com.ORCID 0000-0001-6491-5734
Jeong Rye KimDepartment of Radiology, Dankook University Hospital, Dankook University College of Medicine, Cheonan, Republic of Korea.ORCID 0000-0001-6762-4174
Jae-Yeon HwangDepartment of Radiology, Research Institute for Convergence of Biomedical Science and Technology, Pusan National University Yangsan Hospital, Pusan National University School of Medicine, Yangsan, Republic of Korea.ORCID 0000-0003-2777-3444
Jin-Ho ChoiDepartment of Pediatrics, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea.ORCID 0000-0003-1196-7826
Jisun HwangDepartment of Radiology, Ajou University Hospital, Ajou University School of Medicine, Suwon, Republic of Korea.ORCID 0000-0002-7593-2246
Jaewon LeeVUNO Inc., Seoul, Republic of Korea.ORCID 0000-0002-8039-6222
Jinkyeong SungVUNO Inc., Seoul, Republic of Korea.ORCID 0000-0003-3546-6081
Kyu-Hwan JungVUNO Inc., Seoul, Republic of Korea.ORCID 0000-0002-6626-6800
Byeonguk BaeVUNO Inc., Seoul, Republic of Korea.ORCID 0000-0003-2309-8517
Ah Young JungDepartment of Radiology and Research Institute of Radiology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea.ORCID 0000-0002-7427-6240
Young Ah ChoDepartment of Radiology and Research Institute of Radiology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea.ORCID 0000-0001-6722-121X
Woo Hyun ShimDepartment of Radiology and Research Institute of Radiology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea.ORCID 0000-0002-7251-2916
Boram BakUniversity of Ulsan Foundation for Industry Cooperation, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea.ORCID 0000-0003-0409-6292
Jin Seong LeeDepartment of Radiology and Research Institute of Radiology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea.ORCID 0000-0002-8470-4595
Ulsan College · KRAjou University Hospital · KRDankook University Hospital · KRUniversity of Ulsan · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo develop a deep-learning-based bone age prediction model optimized for Korean children and adolescents and evaluate its feasibility by comparing it with a Greulich-Pyle-based deep-learning model. MATERIALS AND

methodsA convolutional neural network was trained to predict age according to the bone development shown on a hand radiograph (bone age) using 21036 hand radiographs of Korean children and adolescents without known bone development-affecting diseases/conditions obtained between 1998 and 2019 (median age [interquartile range {IQR}], 9 [7-12] years; male:female, 11794:9242) and their chronological ages as labels (Korean model). We constructed 2 separate external datasets consisting of Korean children and adolescents with healthy bone development (Institution 1: n = 343; median age [IQR], 10 [4-15] years; male: female, 183:160; Institution 2: n = 321; median age [IQR], 9 [5-14] years; male: female, 164:157) to test the model performance. The mean absolute error (MAE), root mean square error (RMSE), and proportions of bone age predictions within 6, 12, 18, and 24 months of the reference age (chronological age) were compared between the Korean model and a commercial model (VUNO Med-BoneAge version 1.1; VUNO) trained with Greulich-Pyle-based age as the label (GP-based model).

resultsCompared with the GP-based model, the Korean model showed a lower RMSE (11.2 vs. 13.8 months;

conclusionThe Korean model trained using the chronological ages of Korean children and adolescents without known bone development-affecting diseases/conditions as labels performed better in bone age assessment than the GP-based model in the Korean pediatric population. Further validation is required to confirm its accuracy.

Indexed as

Artificial IntelligenceDeep LearningAdolescentAge Determination by SkeletonChildFemaleHumansInfantMaleRadiographyRepublic of KoreaBone ageConvolutional neural networkDeep-learningPediatrics

Identifiers

PMID37899524
PMCPMC10613838
OpenAlexW4387932679

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.