Evidence map›Paper›PMID 37899431›Full record

ArticleAlzheimer's research & therapy2023

Blockade of adenosine A

Qi Ji, Yang Yang, Yun Xiong, Ying-Jie Zhang, Jun Jiang, Li-Ping Zhou, Xiao-Hui Du, Chun-Xiang Wang, Zhi-Ru Zhu

Open access · goldAbstract read
In one paragraph

Article in Alzheimer's research & therapy, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 13 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Article
  6. Endothelial adenosine AFrontiers in medicine · 2026
    Article
  7. Article
  8. Blockade of AGeroScience · 2025
    Article
  9. Sleep as the Foundation of Brain Health.Seminars in neurology · 2025
    Review
  10. Article
  11. Review
  12. Adenosine and adenosine receptors in metabolic imbalance-related neurological issues.Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie · 2024
    Review
  13. Article
  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Qi Ji *Department of Medical Psychology, Army Medical University, Gaotanyan Street 30, Chongqing, 400038, PR China.
Yang Yang *Department of Medical Psychology, Army Medical University, Gaotanyan Street 30, Chongqing, 400038, PR China.
Yun XiongDepartment of Medical Psychology, Army Medical University, Gaotanyan Street 30, Chongqing, 400038, PR China.
Ying-Jie ZhangDepartment of Medical Psychology, Army Medical University, Gaotanyan Street 30, Chongqing, 400038, PR China.
Jun JiangDepartment of Medical Psychology, Army Medical University, Gaotanyan Street 30, Chongqing, 400038, PR China.
Li-Ping ZhouDepartment of Medical Psychology, Army Medical University, Gaotanyan Street 30, Chongqing, 400038, PR China.
Xiao-Hui DuDepartment of Medical Psychology, Army Medical University, Gaotanyan Street 30, Chongqing, 400038, PR China.
Chun-Xiang WangDepartment of Medical Psychology, Army Medical University, Gaotanyan Street 30, Chongqing, 400038, PR China.
Zhi-Ru ZhuDepartment of Medical Psychology, Army Medical University, Gaotanyan Street 30, Chongqing, 400038, PR China. zhuzr2013@163.com.
Army Medical University · CN

Funding

National Natural Science Foundation of China 31671106National Natural Science Foundation of China 82200865science foundation of army medical university 2019XYY08Scientific Foundation of Chongqing Cstc2019jcyj-msxmX0019
6 · The paper itself

Abstract

backgroundThe over-activation of adenosine A

methodsA transgenic APP/PS1 mouse model of AD amyloidosis was used in this study. Behavioral tests were conducted to observe the protective effects of A

resultsAPP/PS1 mice displayed DG-dependent spatial memory deficits at an early stage. Additionally, impaired LTP and an imbalance in network excitation/inhibition were observed in the DG region of APP/PS1 mice, indicating synaptic structural and functional abnormalities of abGCs. A

conclusionsBlockade of A

Indexed as

Alzheimer DiseaseAdenosineAmyloid beta-Protein PrecursorAnimalsDisease Models, AnimalHippocampusMemory DisordersMiceMice, TransgenicNeuronal PlasticitySpatial MemoryAdenosineAmyloid beta-Protein PrecursorAdenosine A2A receptorsAdult born granule cellsAlzheimer’s diseaseLTPSpatial memory

Identifiers

PMID37899431
PMCPMC10614339
OpenAlexW4388034853

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.