Evidence map›Paper›PMID 37899311›Full record

ArticleChemistry (Weinheim an der Bergstrasse, Germany)2024

Direct Synthesis of N-formamides by Integrating Reductive Amination of Ketones and Aldehydes with CO

Wenyuan Huang, Qingqing Mei, Shaojun Xu, Bing An, Meng He, Jiangnan Li, Yinlin Chen, Xue Han, Tian Luo, Lixia Guo and 9 more

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Chemistry (Weinheim an der Bergstrasse, Germany), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 53% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 4 institutions in 2 countries.

Wenyuan HuangDepartment of Chemistry, University of Manchester, Manchester, M13 9PL, UK.
Qingqing MeiDepartment of Chemistry, University of Manchester, Manchester, M13 9PL, UK.
Shaojun XuDepartment of Chemical Engineering, University of Manchester, Manchester, M13 9PL, UK.
Bing AnDepartment of Chemistry, University of Manchester, Manchester, M13 9PL, UK.
Meng HeDepartment of Chemistry, University of Manchester, Manchester, M13 9PL, UK.
Jiangnan LiDepartment of Chemistry, University of Manchester, Manchester, M13 9PL, UK.
Yinlin ChenDepartment of Chemistry, University of Manchester, Manchester, M13 9PL, UK.
Xue HanDepartment of Chemistry, University of Manchester, Manchester, M13 9PL, UK.
Tian LuoDepartment of Chemistry, University of Manchester, Manchester, M13 9PL, UK.
Lixia GuoDepartment of Chemistry, University of Manchester, Manchester, M13 9PL, UK.
Joseph HurdDepartment of Chemical Engineering, University of Manchester, Manchester, M13 9PL, UK.
Daniel LeeDepartment of Chemical Engineering, University of Manchester, Manchester, M13 9PL, UK.
Evan TillotsonDepartment of Materials, University of Manchester, Manchester, M13 9PL, UK.
Sarah J HaighDepartment of Materials, University of Manchester, Manchester, M13 9PL, UK.
Alex WaltonDepartment of Chemistry, University of Manchester, Manchester, M13 9PL, UK.
Sarah J DayDiamond Light Source Harwell Science Campus, Oxfordshire, OX11 0DE, UK.
Louise S NatrajanDepartment of Chemistry, University of Manchester, Manchester, M13 9PL, UK.
Martin SchröderDepartment of Chemistry, University of Manchester, Manchester, M13 9PL, UK.ORCID https://orcid.org/0000-0001-6992-0700
Sihai YangDepartment of Chemistry, University of Manchester, Manchester, M13 9PL, UK.
University of Manchester · GBRutherford Appleton Laboratory · GBBeijing Normal University · CNPeking University · CN

Funding

European Research Council 742401
6 · The paper itself

Abstract

Formamides are important feedstocks for the manufacture of many fine chemicals. State-of-the-art synthesis of formamides relies on the use of an excess amount of reagents, giving copious waste and thus poor atom-economy. Here, we report the first example of direct synthesis of N-formamides by coupling two challenging reactions, namely reductive amination of carbonyl compounds, particularly biomass-derived aldehydes and ketones, and fixation of CO

Indexed as

MFM-300(Cr)N-formylationReductive aminationssNMRSXPD

Identifiers

PMID37899311
PMCPMC10952134
OpenAlexW4388014012

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.