Evidence map›Paper›PMID 37899243›Full record

ArticleInternal medicine (Tokyo, Japan)2024

Bilateral Nephrectomy for Resistant Hypertension and Secondary Aldosteronism in a Hemodialysis Patient: A Case Report.

Kota Nishihama, Chisa Inoue, Kohei Nishikawa, Yuko Okano, Atsuro Takeshita, Mei Uemura, Taro Yasuma, Toshinari Suzuki, Ryuji Okamoto, Corina N D'Alessandro-Gabazza and 2 more

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In one paragraph

Article in Internal medicine (Tokyo, Japan), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.2field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 1 institution in 1 country.

Kota NishihamaDepartment of Diabetes, Metabolism and Endocrinology, Mie University Graduate School of Medicine, Japan.
Chisa InoueDepartment of Diabetes, Metabolism and Endocrinology, Mie University Graduate School of Medicine, Japan.
Kohei NishikawaDepartment of Nephro-Urologic Surgery and Andrology, Mie University Graduate School of Medicine, Japan.
Yuko OkanoDepartment of Diabetes, Metabolism and Endocrinology, Mie University Graduate School of Medicine, Japan.
Atsuro TakeshitaDepartment of Diabetes, Metabolism and Endocrinology, Mie University Graduate School of Medicine, Japan.
Mei UemuraDepartment of Diabetes, Metabolism and Endocrinology, Mie University Graduate School of Medicine, Japan.
Taro YasumaDepartment of Diabetes, Metabolism and Endocrinology, Mie University Graduate School of Medicine, Japan.
Toshinari SuzukiDepartment of Diabetes, Metabolism and Endocrinology, Mie University Graduate School of Medicine, Japan.
Ryuji OkamotoDepartment of Cardiology and Nephrology, Mie University Graduate School of Medicine, Japan.
Corina N D'Alessandro-GabazzaDepartment of Immunology, Mie University Graduate School of Medicine, Japan.
Esteban C GabazzaDepartment of Immunology, Mie University Graduate School of Medicine, Japan.
Yutaka YanoDepartment of Diabetes, Metabolism and Endocrinology, Mie University Graduate School of Medicine, Japan.
Mie University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A 42-year-old Japanese woman with end-stage renal failure due to hypertension presented with a systolic blood pressure of 160-200 mmHg despite treatment with 4 different antihypertensive agents. The plasma aldosterone concentration (PAC) and plasma renin activity (PRA) were elevated. Adrenal vein sampling suggested bilateral excessive aldosterone secretion, whereas adrenocortical scintigraphy showed right-dominant accumulation. Open bilateral nephrectomy and right adrenalectomy improved the systolic blood pressure, PAC, and PRA. A pathological examination revealed zona glomerulosa hyperplasia but not microaldosteronoma. This report shows that bilateral nephrectomy, not unilateral adrenalectomy, is a potentially effective treatment option for resistant hypertension with an elevated renin-angiotensin-aldosterone system in hemodialysis patients.

Indexed as

HyperaldosteronismHypertensionKidney Failure, ChronicNephrectomyRenal DialysisAdrenalectomyAdultFemaleHumansadrenalectomyhyperaldosteronismnephrectomyresistant hypertension

Identifiers

PMID37899243
PMCPMC11189696
OpenAlexW4387954148

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.