Evidence map›Paper›PMID 37899140›Full record

ArticleDiseases of the esophagus : official journal of the International Society for Diseases of the Esophagus2024

Cytosponge procedures produce fewer respiratory aerosols and droplets than esophagogastroduodenoscopies.

George S D Gordon, Samantha Warburton, Sian Parkes, Abigail Kerridge, Adolfo Parra-Blanco, Jacobo Ortiz-Fernandez-Sordo, Rebecca C Fitzgerald

Open access · hybridAbstract read
In one paragraph

Article in Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

George S D GordonDepartment of Electrical and Electronic Engineering, University of Nottingham, Nottingham, UK.
Samantha WarburtonNIHR Nottingham Biomedical Research Centre, Nottingham University Hospitals NHS Trust and the University of Nottingham, Queens Medical Centre, Derby Road, Nottingham NG7 2UH, UK.
Sian ParkesNIHR Nottingham Biomedical Research Centre, Nottingham University Hospitals NHS Trust and the University of Nottingham, Queens Medical Centre, Derby Road, Nottingham NG7 2UH, UK.
Abigail KerridgeEarly Cancer Institute, Department of Oncology, University of Cambridge, Adrian Way, Cambridge CB2 0XZ, UK.
Adolfo Parra-BlancoNIHR Nottingham Biomedical Research Centre, Nottingham University Hospitals NHS Trust and the University of Nottingham, Queens Medical Centre, Derby Road, Nottingham NG7 2UH, UK.
Jacobo Ortiz-Fernandez-SordoNIHR Nottingham Biomedical Research Centre, Nottingham University Hospitals NHS Trust and the University of Nottingham, Queens Medical Centre, Derby Road, Nottingham NG7 2UH, UK.
Rebecca C FitzgeraldEarly Cancer Institute, Department of Oncology, University of Cambridge, Adrian Way, Cambridge CB2 0XZ, UK.
Nottingham University Hospitals NHS Trust · GBUniversity of Cambridge · GBUniversity of Nottingham · GB

Funding

Cancer Research UKMedical Research Council MR/W014122/1
6 · The paper itself

Abstract

Esophagogastroduodenoscopies (EGD) are aerosol-generating procedures that may spread respiratory pathogens. We aim to investigate the production of airborne aerosols and droplets during Cytosponge procedures, which are being evaluated in large-scale research studies and National Health Service (NHS)implementation pilots to reduce endoscopy backlogs. We measured 18 Cytosponge and 37 EGD procedures using a particle counter (diameters = 0.3-25 μm), taking measurements 10 cm from the mouth. Two particle count analyses were performed: whole procedure and event-based. Direct comparison with duration-standardized EGD procedures shows that Cytosponge procedures produce 2.16× reduction (P < 0.001) for aerosols and no significant change for droplets (P = 0.332). Event-based analysis shows that particle production is driven by throat spray (aerosols: 138.1× reference, droplets: 16.2×), which is optional, and removal of Cytosponge (aerosols: 14.6×, droplets: 62.6×). Cytosponge burping produces less aerosols than EGD (2.82×, P < 0.05). Cytosponge procedures produce significantly less aerosols and droplets than EGD procedures and thus reduce two potential transmission routes for respiratory viruses.

Indexed as

Respiratory Aerosols and DropletsState MedicineAerosolsEndoscopy, Digestive SystemHumansMouthAerosolsendocytoscopyesophagogastroduodenoscopyinfection

Identifiers

PMID37899140
PMCPMC10906705
OpenAlexW4388007605

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.