Evidence map›Paper›PMID 37899088›Full record

ArticleBMJ global health2023

Geospatial patterns of progress towards UNAIDS '95-95-95' targets and community vulnerability in Zambia: insights from population-based HIV impact assessments.

Diego F Cuadros, Tuhin Chowdhury, Masabho Milali, Daniel T Citron, Sulani Nyimbili, Natalie Vlahakis, Theodora Savory, Lloyd Mulenga, Suilanji Sivile, Khozya Davie Zyambo and 1 more

Open access · goldAbstract read
In one paragraph

Article in BMJ global health, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 2 countries.

Diego F CuadrosDigital Epidemiology Laboratory, Digital Futures, University of Cincinnati, Cincinnati, OH, USA diego.cuadros@uc.edu.ORCID 0000-0001-7060-4203
Tuhin ChowdhuryDigital Epidemiology Laboratory, Digital Futures, University of Cincinnati, Cincinnati, OH, USA.
Masabho MilaliDepartment of Population Health, New York University Grossman School of Medicine, New York, New York, USA.
Daniel T CitronDepartment of Population Health, New York University Grossman School of Medicine, New York, New York, USA.
Sulani NyimbiliCentre for Infectious Disease Research in Zambia (CIDRZ), Lusaka, Zambia.
Natalie VlahakisCentre for Infectious Disease Research in Zambia (CIDRZ), Lusaka, Zambia.
Theodora SavoryCentre for Infectious Disease Research in Zambia (CIDRZ), Lusaka, Zambia.
Lloyd MulengaNational HIV Program, Ministry of Health, Lusaka, Zambia.
Suilanji SivileNational HIV Program, Ministry of Health, Lusaka, Zambia.
Khozya Davie ZyamboNational HIV Program, Ministry of Health, Lusaka, Zambia.ORCID 0000-0002-3813-2784
Anna BershteynDepartment of Population Health, New York University Grossman School of Medicine, New York, New York, USA.
Centre for Infectious Disease Research in Zambia · ZMMinistry of Health · ZMNew York University · USUniversity of Cincinnati · US

Funding

Can mental health services break the cycle perpetuating HIV hotspots in sub-Saharan Africa?R01MH124478 · NIMH · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI BERSHTEYN, ANNA · 2021 to 2025
$3.2M
Rapid Tests for Recent Infection (RTRI) for Precision Public Health in Sub-Saharan Africa: Next-Generation Strategies Amid Changing HIV EpidemiologyR01AI174932 · NIAID · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI Ronald Scott Braithwaite · 2023 to 2026
$3.0M
When are in-person HIV services worth the risk of COVID-19 and other communicable illnesses? Optimizing choices when virtual services are less effectiveR01MH130238 · NIMH · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI BERSHTEYN, ANNA · 2022 to 2024
$2.2M
NIAID NIH HHS R01 AI174932NIMH NIH HHS R01 MH124478NIMH NIH HHS R01 MH130238
6 · The paper itself

Abstract

introductionIn sub-Saharan Africa, HIV/AIDS remains a leading cause of death. The UNAIDS established the '95-95-95' targets to improve HIV care continuum outcomes. Using geospatial data from the Zambia Population-based HIV Impact Assessment (ZAMPHIA), this study aims to investigate geospatial patterns in the '95-95-95' indicators and individual-level determinants that impede HIV care continuum in vulnerable communities, providing insights into the factors associated with gaps.

methodsThis study used data from the 2016 ZAMPHIA to investigate the geospatial distribution and individual-level determinants of engagement across the HIV care continuum in Zambia. Gaussian kernel interpolation and optimised hotspot analysis were used to identify geospatial patterns in the HIV care continuum, while geospatial k-means clustering was used to partition areas into clusters. The study also assessed healthcare availability, access and social determinants of healthcare utilisation. Multiple logistic regression models were used to examine the association between selected sociodemographic and behavioural covariates and the three main outcomes of study.

resultsVaried progress towards the '95-95-95' targets were observed in different regions of Zambia. Each '95' displayed a unique geographical pattern, independent of HIV prevalence, resulting in four distinct geographical clusters. Factors associated with gaps in the '95s' include younger age, male sex, and low wealth, with younger individuals having higher odds of not being on antiretroviral therapy and having detectable viral loads.

conclusionsOur study revealed significant spatial heterogeneity in the HIV care continuum in Zambia, with different regions exhibiting unique geographical patterns and levels of performance in the '95-95-95' targets, highlighting the need for geospatial tailored interventions to address the specific needs of different subnational regions. These findings underscore the importance of addressing differential regional gaps in HIV diagnosis, enhancing community-level factors and developing innovative strategies to improve local HIV care continuum outcomes.

Indexed as

HIVHIV InfectionsAfrica South of the SaharaDelivery of Health CareHumansMaleZambiaAIDSEpidemiologyGeographic information systemsHIV

Identifiers

PMID37899088
PMCPMC10619088
OpenAlexW4388035565

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.