Evidence map›Paper›PMID 37898807›Full record

ArticleChild and adolescent psychiatry and mental health2023

Autism spectrum disorder prevalence in Italy: a nationwide study promoted by the Ministry of Health.

Maria Luisa Scattoni, Laura Maria Fatta, Martina Micai, Maria Enrica Sali, Marina Bellomo, Tommaso Salvitti, Francesca Fulceri, Angela Castellano, Massimo Molteni, Giovanna Gambino and 3 more

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Child and adolescent psychiatry and mental health, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06692946 (Evaluation of the Clinical Efficacy of Cooperative Parent-Mediated Therapy), which is not on this map. Cited by 32 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed, 2 pooled it
7.6field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06692946 nacompletednot on this map

Evaluation of the Clinical Efficacy of Cooperative Parent-Mediated Therapy (Cooperative-PMT) in Preschool and School-Aged Children With ASD Within the "Autism in Re.Te: Let's Not Leave Them Alone" - Social Project

TypeinterventionalSponsorALESSANDRA CARTARan2021 to 2024Enrolled50ConditionsAutism Spectrum Disorder, Parent-TrainingArmsCooperative Parent-Mediated therapy, Treatement as Usual
3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 2 syntheses or guidelines pooled it, 43 citations in OpenAlex.

  1. Pooled it
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  7. Observational
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  10. Prevalence of OSA Risk and Bruxism in Children With Autism Spectrum Disorders.Autism research : official journal of the International Society for Autism Research · 2026
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 6 institutions in 2 countries.

Maria Luisa ScattoniResearch Coordination and Support Service, Istituto Superiore di Sanità, Rome, Italy. marialuisa.scattoni@iss.it.
Laura Maria FattaResearch Coordination and Support Service, Istituto Superiore di Sanità, Rome, Italy.
Martina MicaiResearch Coordination and Support Service, Istituto Superiore di Sanità, Rome, Italy.
Maria Enrica SaliIRCCS Eugenio Medea, Parini, Italy.
Marina BellomoUOC ASP Palermo, Palermo, Italy.
Tommaso SalvittiResearch Coordination and Support Service, Istituto Superiore di Sanità, Rome, Italy.
Francesca FulceriResearch Coordination and Support Service, Istituto Superiore di Sanità, Rome, Italy.
Angela CastellanoASL Roma 1, Rome, Italy.
Massimo MolteniIRCCS Eugenio Medea, Parini, Italy.
Giovanna GambinoUOC ASP Palermo, Palermo, Italy.
Manuel PosadaInstituto de Salud Carlos III, Madrid, Spain.
Giovanna RomanoMinistero della Salute, Rome, Italy.
Maria PuopoloDepartment of Neuroscience, Istituto Superiore di Sanità, Rome, Italy.
Istituto Superiore di Sanità · ITIRCCS Eugenio Medea · ITUniversity of Palermo · ITASL Roma · ITEscuela Nacional de Sanidad · ESMinistero della Salute · IT

Funding

European Parliament SANCO/2014/C2/035Ministero della Salute 6S02
6 · The paper itself

Abstract

backgroundThis nationwide study aimed to estimate Autism Spectrum Disorder (ASD) prevalence in 7-9-year-old Italian children. Promoted by Italy's Ministry of Health and coordinated by the National Observatory for Autism at the National Institute of Health, it covered schools in northern (Lecco and Monza-Brianza), central (Rome and its province), and southern (Palermo and its province) regions from February 24, 2016, to February 23, 2018, using a multi-stage approach defined by the European Union's ASD network.

methodsPhase one identified ASD-diagnosed children in mainstream schools through local Ministry of Education (MoE) disability registries. Phase two had a subset of schools screen 7-9-year-olds using the Social Communication Questionnaire-Life version (SCQ-L). Those with SCQ-L scores of 15 + underwent clinical consultation for ASD symptoms, cognitive abilities, and life skills. To counter potential false negatives, 20% scoring 11-14 were randomly assessed via Autism Diagnostic Interview-Revised (ADI-R).

resultsMoE data revealed 9.8 per 1000 certified ASD children in the north, 12.2 in the central, and 10.3 in the south. In phase two, 35,823 SCQ-L questionnaires were distributed across 198 schools (northern: 11,190 in 49 schools, central: 13,628 in 87 schools, southern: 11,005 in 62 schools). Of SCQ-L respondents, 2.4% (n = 390) scored above the 15 cutoff. Among these, 100 had ASD diagnoses, and 50 had other diagnoses. Among 115 families assessed, 16.5% (n = 19) received ASD diagnoses.

conclusionsThe estimated prevalence of ASD in Italy was 13.4 (11.3-16.0) per 1,000 children aged 7-9 years, with a male-to-female ratio of 4.4:1. It will guide national policies in enhancing services tailored to the specific needs of autistic children.

Indexed as

Autism spectrum disorderEpidemiologyMultistage screeningPrevalence estimate

Identifiers

PMID37898807
PMCPMC10613370
OpenAlexW4388035417

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.