Evidence map›Paper›PMID 37898802›Full record

ArticleBMC oral health2023

Evaluating the effect of poly (amidoamine) treated bioactive glass nanoparticle incorporated in universal adhesive on bonding to artificially induced caries affected dentin.

Akhil C Rao, Vijay Venkatesh Kondas, Vidyashree Nandini, Ravi Kirana, Pradeep Kumar Yadalam, Rajalakshmanan Eswaramoorthy

Abstract read
In one paragraph

Article in BMC oral health, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Akhil C RaoDepartment of Conservative Dentistry and Endodontics, School Of Dental Sciences Krishna Institute, Malkapur, Karad, Maharashtra, 415110, India.
Vijay Venkatesh KondasDepartment of Conservative Dentistry and Endodontics, SRM Kattankulathur Dental College and Hospital, SRM Institute Of Science And Technology, SRM Nagar, Kattankulathur, Kanchipuram, Chennai, Tamilnadu, 603203, India. vijayvek@srmist.edu.in.
Vidyashree NandiniDepartment of Prosthodontics and Implantology, SRM Kattankulathur Dental College and Hospital, SRM Institute Of Science And Technology, SRM Nagar, Kattankulathur, Kanchipuram, Chennai, Tamilnadu, 603203, India.
Ravi KiranaHigh Temperature Material Processing Laboratory, Department of Physics and Nanotechnology, SRM Institute of Science and Technology, Kattankulathur, Chengalpattu, Tamil Nadu, 603203, India.
Pradeep Kumar YadalamDepartment of Periodontics, Saveetha Institute of Medical and Technical Sciences, Saveetha Dental College, Saveetha University, Chennai, 600077, India.
Rajalakshmanan EswaramoorthyDepartment of Biomaterials, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences (SIMATS), Chennai, India. rajalakshmanan.e@gmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe purpose of this study was to evaluate remineralisation and its effect on microtensile bond-strength of artificially induced caries affected dentin (CAD) when treated with a commercial universal adhesive modified with poly(amidoamine) dendrimer (PAMAM) loaded mesoporous bioactive glass nanoparticles (A-PMBG). MATERIAL AND

methodsMesoporous bioactive glass nanoparticles (MBG) were synthesised using sol-gel process, where PAMAM was loaded (P-MBG) and added to commercial adhesive at different weight percentages (0.2, 0.5, 1 and 2 wt%). First, rheological properties of commercial and modified adhesives were evaluated. The effect of remineralization/hardness and microtensile bond-strength (MTBs) of those samples that mimicked the rheological properties of commercial adhesives were evaluated using Vickers hardness tester and universal testing machine respectively. Scanning-Electron microscope was used to visualize failed samples of MTBs and remineralization samples. Both evaluations were carried out at 1-,3 and 6-month intervals, samples being stored in stimulated salivary fluid during each time interval.

resultsAddition of nanoparticles altered the rheological properties. With increase in the weight percentage of nanoparticles in commercial adhesive, there was significant increase in degree of conversion, viscosity and sedimentation rate (p < 0.05). The 0.2 and 0.5 wgt% groups closely mimicked the properties of commercial adhesive and were evaluated for remineralization and MTBs. After 6 months, 0.2wgt% group showed increased MTBs (p < 0.05) and 0.5wgt% group increased remineralization/hardness (p < 0.05).

conclusionThe complex of PAMAM-MBG-Universal adhesive can remineralize the demineralised CAD thereby improving its bond-strength when evaluated for up to 6-months.

Indexed as

Dental BondingDental CariesNanoparticlesDental Caries SusceptibilityDental CementsDentinHumansMaterials TestingResin CementsTensile StrengthDental CementsResin CementsCaries-affected dentinPAMAM dendrimerPAMAM-loaded bioactive glass nanoparticlesRemineralizing demineralized dentinUniversal adhesive

Identifiers

PMID37898802
PMCPMC10612299

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.