Evidence map›Paper›PMID 37898749›Full record

ReviewMalaria journal2023

Exploring the feasibility of introducing triple artemisinin-based combination therapy in the malaria treatment policy in Vietnam.

Van Anh Thi Cao, Thieu Quang Nguyen, Duong Le Quyen, Wouter P C Boon, Ellen H M Moors, Arjen M Dondorp, Freek de Haan, Chanaki Amaratunga

Abstract readReview
In one paragraph

Review in Malaria journal, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. A clinical drug-drug interaction assessment using physiologically based pharmacokinetic modeling: a case study with chloroquine and colchicine.Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas · 2026
    Article
  2. Article
  3. Article
  4. Artemisinin-resistant malaria.Clinical microbiology reviews · 2024
    Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Van Anh Thi Cao *The University of North Carolina Project Office, Hanoi, Vietnam. caovananhph@gmail.com.
Thieu Quang Nguyen *National Institute of Malariology, Parasitology and Entomology, Hanoi, Vietnam.
Duong Le QuyenWorld Mosquito Program, Ho Chi Minh, Vietnam.
Wouter P C BoonCopernicus Institute of Sustainable Development, Utrecht University, Utrecht, The Netherlands.
Ellen H M MoorsCopernicus Institute of Sustainable Development, Utrecht University, Utrecht, The Netherlands.
Arjen M DondorpMahidol Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand.
Freek de HaanCopernicus Institute of Sustainable Development, Utrecht University, Utrecht, The Netherlands.
Chanaki AmaratungaMahidol Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThis study investigates the processes regarding changing malaria treatment policies in Vietnam. Moreover, it explores the feasibility of introducing triple artemisinin-based combination therapy (TACT) in Vietnam to support the national malaria control and elimination plan.

methodsData were collected via 12 in-depth interviews with key stakeholders, combined with a review of policy documents.

resultsTACT is considered as a useful backup strategy in case future treatment failures with current artemisinin-based combination therapy (ACT) would occur. Moreover, TACT is also considered as a promising strategy to prevent the re-establishment of malaria. However, regulatory procedures and implementation timelines for TACT were expected to be lengthy. Therefore, strategies to engage national decision-makers, regulators, and suppliers should be initiated soon, stipulating the benefits of TACT deployment. In Vietnam, a procedure to apply for an import permit without registration that has previously been applied to the introduction of artesunate-pyronaridine was proposed to accelerate the introduction of TACT. Global-level support through the World Health Organization recommendations and prequalification were considered critical for supporting the introduction of TACT in Vietnam.

conclusionsAppropriate approach strategies and early stakeholder engagement will be needed to accelerate the introduction of TACT in Vietnam.

Indexed as

AntimalarialsArtemisininsMalariaMalaria, FalciparumDrug Therapy, CombinationFeasibility StudiesHumansPlasmodium falciparumPolicyVietnamAntimalarialsartemisininArtemisininsDrug resistanceIntroduction strategiesTriple artemisinin-based combination therapy (TACT)

Identifiers

PMID37898749
PMCPMC10613363

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.