Evidence map›Paper›PMID 37898638›Full record

ArticleNature communications2023

Emergence of cortical network motifs for short-term memory during learning.

Xin Wei Chia, Jian Kwang Tan, Lee Fang Ang, Tsukasa Kamigaki, Hiroshi Makino

Open access · goldAbstract read
In one paragraph

Article in Nature communications, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Decomposing the modulation of interactions between neuronal populations.bioRxiv : the preprint server for biology · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Xin Wei ChiaLee Kong Chian School of Medicine, Nanyang Technological University, Singapore, 308232, Singapore.ORCID 0000-0002-3949-9131
Jian Kwang Tan *Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, 308232, Singapore.ORCID 0000-0002-1579-6430
Lee Fang Ang *Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, 308232, Singapore.ORCID 0009-0008-7290-7265
Tsukasa KamigakiLee Kong Chian School of Medicine, Nanyang Technological University, Singapore, 308232, Singapore.ORCID 0000-0002-5184-708X
Hiroshi MakinoLee Kong Chian School of Medicine, Nanyang Technological University, Singapore, 308232, Singapore. hmakino@ntu.edu.sg.ORCID 0000-0003-1591-8001
Nanyang Technological University · SG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Learning of adaptive behaviors requires the refinement of coordinated activity across multiple brain regions. However, how neural communications develop during learning remains poorly understood. Here, using two-photon calcium imaging, we simultaneously recorded the activity of layer 2/3 excitatory neurons in eight regions of the mouse dorsal cortex during learning of a delayed-response task. Across learning, while global functional connectivity became sparser, there emerged a subnetwork comprising of neurons in the anterior lateral motor cortex (ALM) and posterior parietal cortex (PPC). Neurons in this subnetwork shared a similar choice code during action preparation and formed recurrent functional connectivity across learning. Suppression of PPC activity disrupted choice selectivity in ALM and impaired task performance. Recurrent neural networks reconstructed from ALM activity revealed that PPC-ALM interactions rendered choice-related attractor dynamics more stable. Thus, learning constructs cortical network motifs by recruiting specific inter-areal communication channels to promote efficient and robust sensorimotor transformation.

Indexed as

Memory, Short-TermMotor CortexAnimalsMiceNeural Networks, ComputerNeuronsParietal Lobe

Identifiers

PMID37898638
PMCPMC10613236
OpenAlexW4388035083

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.