ReviewAgeing research reviews2023
Understanding the health effects of caregiving stress: New directions in molecular aging.
Review in Ageing research reviews, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
29 citing papers in PubMed.
- Life's Simple 7, depressive symptoms, cognitive performance, and their associations with all-cause mortality among middle-aged urban adults.GeroScience · 2026Article
- Adult day services, leisure time satisfaction, and psychosocial well-being among dementia caregivers.The Gerontologist · 2026Article
- Interpersonal emotion regulation in dementia: Diagnostic differences and associations with caregiver mental health.Emotion (Washington, D.C.) · 2026Article
- Role Captivity in Former Dementia Caregivers: Constrained Choice, Role Engulfment and Caregiver Wellbeing in Ageing Care.Geriatrics (Basel, Switzerland) · 2026Article
- Interacting and joint effects of frailty and depressive symptoms in relation to risk of cardio-oncology comorbidity in older adults from three prospective cohorts.BMC geriatrics · 2026Article
- Personality moderates immunological and functional consequences of caregiver burden.Health psychology : official journal of the Division of Health Psychology, American Psychological Association · 2026Article
- Advancing women's mental health: Recommendations from a National Academies of Sciences, Engineering, and Medicine workshop.PNAS nexus · 2026Article
- Social connection and cognitive health: A review of concepts, measures, and research priorities.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026Review
- Review
- Virtual community-based interventions for family caregivers of people with dementia: A scoping review protocol.PloS one · 2026Article
- Trajectories of family resilience among caregivers of older adults with dementia: a longitudinal study in community-based geriatric care settings.Frontiers in public health · 2026Article
- REMINDER program: a randomized controlled trial protocol of a neuropsychological intervention for lifestyle modification in older adults at risk of dementia.BMC geriatrics · 2025Article
- Low-Tech Telemedicine Reduces Caregiver Burden and Improves Outcomes in Older Adults with Chronic Diseases: Results from a Prospective Study in Romania.Healthcare (Basel, Switzerland) · 2025Article
- Low-Intensity Virtual Reality Exercise for Caregivers of People with Mild Cognitive Impairment: A Pilot Study.Journal of functional morphology and kinesiology · 2025Article
- Psychosocial stressors and cognitive function: An analysis using data from the English longitudinal study of ageing.The journal of prevention of Alzheimer's disease · 2025Article
- Relationship between cellular aging, perceived stress, and cardiometabolic disease risk in Black family caregivers of persons with dementia.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025Article
- Intersecting race/ethnicity and gender in physiological dysregulation profiles and associations with socioeconomic status among older adults in the United States.SSM - population health · 2025Article
- Factors that influence the preferences for telehealth among family caregivers of disabled elders: a qualitative study.International journal of nursing studies advances · 2025Article
- Family Caregiver Perspectives on Digital Methods to Measure Stress: Qualitative Descriptive Study.Journal of medical Internet research · 2025Article
- Stress and Hypertension Among African American Female Family Caregivers of Persons Living With Alzheimer Disease and Related Dementias: Protocol for a Pilot Internet-Based Randomized Controlled Trial.JMIR research protocols · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
Abstract
Dementia caregiving has been linked to multiple health risks, including infectious illness, depression, anxiety, immune dysregulation, weakened vaccine responses, slow wound healing, hypertension, cardiovascular disease, metabolic syndrome, diabetes, frailty, cognitive decline, and reduced structural and functional integrity of the brain. The sustained overproduction of proinflammatory cytokines is a key pathway behind many of these risks. However, contrasting findings suggest that some forms of caregiving may have beneficial effects, such as maintaining caregivers' health and providing a sense of meaning and purpose which, in turn, may contribute to lower rates of functional decline and mortality. The current review synthesizes these disparate literatures, identifies methodological sources of discrepancy, and integrates caregiver research with work on aging biomarkers to propose a research agenda that traces the mechanistic pathways of caregivers' health trajectories with a focus on the unique stressors facing spousal caregivers as compared to other informal caregivers. Combined with a focus on psychosocial moderators and mechanisms, studies using state-of-the-art molecular aging biomarkers such as telomere length, p16
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.