Evidence map›Paper›PMID 37897873›Full record

ArticleEnvironment international2023

Associations between short-term ambient temperature exposure and emergency department visits for amphetamine, cocaine, and opioid use in California from 2005 to 2019.

Howard H Chang, Haisu Zhang, Amanda D Latimore, Brian P Murray, Rohan R D'Souza, Noah Scovronick, Matthew O Gribble, Stefanie T Ebelt

Open access · goldAbstract read
In one paragraph

Article in Environment international, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 2 pooled it
3.0field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 2 syntheses or guidelines pooled it, 19 citations in OpenAlex.

  1. Building the model: a review of input structures in extreme temperature-health.Environmental health : a global access science source · 2026
    Pooled it
  2. Pooled it
  3. Socioenvironmental disasters and the dialectics of overdose mortality.The International journal on drug policy · 2026
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Weather-Related Trends in Drug Use Incidents Aboard Transit Vehicles.Journal of urban health : bulletin of the New York Academy of Medicine · 2026
    Article
  10. Heat exposure and drug overdose mortality in the USA.Addiction (Abingdon, England) · 2026
    Observational
  11. Article
  12. Article
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  14. Article
  15. Article
  16. Article
  17. Article
  18. Exploring the Nexus of Climate Change and Substance Abuse: A Scoping Review.International journal of environmental research and public health · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Howard H ChangDepartment of Biostatistics and Bioinformatics, Emory University, Atlanta, GA, USA; Gangarosa Department of Environmental Health, Emory University, Atlanta, GA, USA. Electronic address: howard.chang@emory.edu.
Haisu ZhangGangarosa Department of Environmental Health, Emory University, Atlanta, GA, USA.
Amanda D LatimoreCenter for Addiction Research and Effective Solutions, American Institutes for Research, Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.
Brian P MurrayEmergency Medicine, Boonshoft School of Medicine, Wright State University, Dayton, OH, USA.
Rohan R D'SouzaDepartment of Biostatistics and Bioinformatics, Emory University, Atlanta, GA, USA.
Noah ScovronickGangarosa Department of Environmental Health, Emory University, Atlanta, GA, USA.
Matthew O GribbleDepartment of Epidemiology, University of Alabama at Birmingham, Birmingham, AL, USA.
Stefanie T EbeltGangarosa Department of Environmental Health, Emory University, Atlanta, GA, USA.
Emory University · USAmerican Institutes for Research · USUniversity of Alabama at Birmingham · USWright State University · US

Funding

Pilot Project ProgramP30ES019776 · NIEHS · EMORY UNIVERSITY · PI William Michael Caudle · 2013 to 2026
$22.6M
Data Integration Methods for Environmental Exposures with Applications to Air Pollution and Asthma MorbidityR01ES027892 · NIEHS · EMORY UNIVERSITY · PI CHANG, HOWARD H · 2017 to 2021
$2.7M
NIEHS NIH HHS P30 ES019776NIEHS NIH HHS R01 ES027892NIOSH CDC HHS T42 OH008429
6 · The paper itself

Abstract

Substance use disorder is a growing public health challenge in the United States. People who use drugs may be more vulnerable to ambient heat due to the effects of drugs on thermoregulation and their risk environment. There have been limited population-based studies of ambient temperature and drug-related morbidity. We examined short-term associations between daily ambient temperature and emergency department (ED) visits for use or overdose of amphetamine, cocaine and opioids in California during the period 2005 to 2019. Daily ZIP code-level maximum, mean, and minimum temperature exposures were derived from 1-km data Daymet products. A time-stratified case-crossover design was used to estimate cumulative non-linear associations of daily temperature for lag days 0 to 3. Stratified analyses by patient sex, race, and ethnicity were also conducted. The study included over 3.4 million drug-related ED visits. We found positive associations between daily temperature and ED visits for all outcomes examined. An increase in daily mean temperature from the 50th to the 95th percentile was associated with ED visits for amphetamine use (OR = 1.072, 95% CI: 1.058, 1.086), cocaine use (OR = 1.044, 95% CI: 1.021, 1.068 and opioid use (OR = 1.041, 95% CI: 1.025, 1.057). Stronger positive associations were also observed for overdose: amphetamine overdose (OR = 1.150, 95% CI: 1.085, 1.218), cocaine overdose (OR = 1.159, 95% CI: 1.053, 1.276), and opioid overdose (OR = 1.079, 95% CI: 1.054, 1.106). In summary, people who use stimulants and opioids may be a subpopulation sensitive to short-term higher ambient temperature. Mitigating heat exposure can be considered in harm reduction strategies in response to the substance use epidemic and global climate change.

Indexed as

CocaineDrug OverdoseAmphetamineAnalgesics, OpioidCaliforniaCross-Over StudiesEmergency Service, HospitalHumansTemperatureUnited StatesAmphetamineAnalgesics, OpioidCocaineCocaineHeatOpioidOverdose stimulantSubstance useTemperature

Identifiers

PMID37897873
PMCPMC10712015
OpenAlexW4387036108

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.