Evidence map›Paper›PMID 37897218›Full record

ArticleAmerican journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists2024

Understanding clinical implementation coordinators' experiences in deploying evidence-based interventions.

Sara E Hernandez, Demetrius Solomon, Jukrin Moon, Vishala Parmasad, Douglas Wiegmann, Nick T Bennett, Ryan S Ferren, Alec J Fitzsimmons, Alexander J Lepak, John C O'Horo and 3 more

Open access · greenAbstract readMulticenter Study
In one paragraph

Article in American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Direct Outreach Meetings Increase Primary Care Utilization of Psychiatry Access Programs.The journal of behavioral health services & research · 2025
    Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 6 institutions in 1 country.

Sara E HernandezSchool of Pharmacy, University of Wisconsin-Madison, Madison, WI, USA.
Demetrius SolomonDepartment of Industrial and Systems Engineering, University of Wisconsin-Madison, Madison, WI, USA.
Jukrin MoonSchool of Pharmacy, University of Wisconsin-Madison, Madison, WI, USA.
Vishala ParmasadSchool of Medicine and Public Health, University of Wisconsin-Madison, Madison, WI, USA.
Douglas WiegmannDepartment of Industrial and Systems Engineering, University of Wisconsin-Madison, Madison, WI, USA.
Nick T BennettAntimicrobial Stewardship Program, Saint Luke's Health System, Kansas City, MO, USA.
Ryan S FerrenUniversity of Texas Medical Branch, Galveston, TX, USA.
Alec J FitzsimmonsDepartment of Medical Research, Gundersen Health System, La Crosse, WI, USA.
Alexander J LepakSchool of Medicine and Public Health, University of Wisconsin-Madison, Madison, WI, USA.
John C O'HoroMayo Foundation for Medical Education and Research, Rochester, MN, USA.
Aurora E Pop-VicasSchool of Medicine and Public Health, University of Wisconsin-Madison, Madison, WI, USA.
Lucas T SchulzDepartment of Pharmacy, University of Wisconsin Health, Madison, WI, USA.
Nasia SafdarSchool of Medicine and Public Health, University of Wisconsin-Madison, Madison, WI, USA.
University of Wisconsin–Madison · USGundersen Health System · USMayo Clinic · USSaint Luke's Health System · USThe University of Texas Medical Branch at Galveston · USUniversity of Wisconsin Health · US

Funding

University of Wisconsin Institute for Clinical and Translational ResearchUL1TR002373 · NCATS · UNIVERSITY OF WISCONSIN-MADISON · PI ELIZABETH S BURNSIDE, Allan R. Brasier · 2017 to 2026
$75.9M
Fluoroquinolone Restriction for the Prevention of C. difficile Infection (CDI)_the FIRST Trial.R01HS026226 · AHRQ · UNIVERSITY OF WISCONSIN-MADISON · PI SAFDAR, NASIA · 2018 to 2022
$2.5M
AHRQ HHS R01 HS026226NCATS NIH HHS UL1 TR002373
6 · The paper itself

Abstract

purposeThe fluoroquinolone restriction for the prevention of Clostridioides difficile infection (FIRST) trial is a multisite clinical study in which sites carry out a preauthorization process via electronic health record-based best-practice alert (BPA) to optimize the use of fluoroquinolone antibiotics in acute care settings. Our research team worked closely with clinical implementation coordinators to facilitate the dissemination and implementation of this evidence-based intervention. Clinical implementation coordinators within the antibiotic stewardship team (AST) played a pivotal role in the implementation process; however, considerable research is needed to further understand their role. In this study, we aimed to (1) describe the roles and responsibilities of clinical implementation coordinators within ASTs and (2) identify facilitators and barriers coordinators experienced within the implementation process.

methodsWe conducted a directed content analysis of semistructured interviews, implementation diaries, and check-in meetings utilizing the conceptual framework of middle managers' roles in innovation implementation in healthcare from Urquhart et al.

resultsClinical implementation coordinators performed a variety of roles vital to the implementation's success, including gathering and compiling information for BPA design, preparing staff, organizing meetings, connecting relevant stakeholders, evaluating clinical efficacy, and participating in the innovation as clinicians. Coordinators identified organizational staffing models and COVID-19 interruptions as the main barriers. Facilitators included AST empowerment, positive relationships with staff and oversight/governance committees, and using diverse implementation strategies.

conclusionWhen implementing healthcare innovations, clinical implementation coordinators facilitated the implementation process through their roles and responsibilities and acted as strategic partners in improving the adoption and sustainability of a fluoroquinolone preauthorization protocol.

Indexed as

COVID-19Evidence-Based MedicineDelivery of Health CareFluoroquinolonesHumansModels, OrganizationalFluoroquinolonesantibiotic stewardshipbest-practice alertclinical decision support systemsimplementation sciencemiddle management

Identifiers

PMID37897218
PMCPMC11484602
OpenAlexW4387994050

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.