Evidence map›Paper›PMID 37897138›Full record

SynthesisNeurogastroenterology and motility2024

A systematic review and meta-analysis of diet and nutrient intake in adults with irritable bowel syndrome.

Diego Izquierdo Veraza, Gerardo Calderon, Claire Jansson-Knodell, Rawan Aljaras, Erin D Foster, Huiping Xu, Annabel Biruete, Andrea Shin

Open access · hybridAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Neurogastroenterology and motility, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
3.9field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 14 citations in OpenAlex.

  1. Trial
  2. Article
  3. Application of a food trigger score to identify common dietary triggers among Saudi adults with irritable bowel syndrome.Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association · 2026
    Article
  4. Review
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 6 institutions in 1 country.

Diego Izquierdo VerazaDepartment of Medicine, Indiana University School of Medicine, Indianapolis, Indiana, USA.
Gerardo CalderonDepartment of Medicine, Indiana University School of Medicine, Indianapolis, Indiana, USA.
Claire Jansson-KnodellDivision of Gastroenterology and Hepatology, Department of Medicine, Indiana University School of Medicine, Indianapolis, Indiana, USA.
Rawan AljarasDepartment of Medicine, Indiana University School of Medicine, Indianapolis, Indiana, USA.
Erin D FosterUC Berkeley Library, University of California Berkeley, Berkeley, California, USA.
Huiping XuDepartment of Biostatistics, Indiana University School of Medicine, Indianapolis, Indiana, USA.
Annabel BirueteDepartment of Nutrition and Dietetics, Indiana University-Purdue University Indianapolis, Indianapolis, Indiana, USA.
Andrea ShinDivision of Gastroenterology and Hepatology, Department of Medicine, Indiana University School of Medicine, Indianapolis, Indiana, USA.ORCID https://orcid.org/0000-0001-7284-3398
Indiana University School of MedicineCleveland Clinic · USMayo Clinic · USUniversity of California, Berkeley · USUniversity of California, Los Angeles · USUniversity of Indianapolis · US

Funding

Fecal microbiota, short chain fatty acids, bile acids, and colonic transit in Irritable Bowel SyndromeK23DK122015 · NIDDK · INDIANA UNIVERSITY INDIANAPOLIS · PI SHIN, ANDREA · 2019 to 2022
$812k
NIDDK NIH HHS K23 DK122015NIDDK NIH HHS K23DK122015NIH HHS
6 · The paper itself

Abstract

backgroundNumerous individual and environmental factors including diet may play an important role in the pathophysiology of irritable bowel syndrome (IBS). It is unclear to what degree dietary intake is affected in individuals with IBS. We aimed to perform a systematic review and meta-analysis to summarize dietary intake of adults with IBS and to compare dietary intake between adults with IBS and non-IBS controls.

methodsOvid MEDLINE, Embase, Cochrane, CINAHL, and Scopus were searched through February 2023 for clinical trials and observational studies measuring usual diet in adults with IBS. Pooled weighted averages were estimated for total energy, macronutrient, and micronutrient data. Mean differences (MD) in nutrient intake were estimated for adults with IBS versus non-IBS controls using a random effects model. Heterogeneity was assessed by the inconsistency index (I2). KEY

resultsSixty-three full-text articles were included in the review of which 29 studies included both IBS and control subjects. Nutrients not meeting the recommended intake level for any dietary reference values in the IBS population were fiber and vitamin D. Meta-regression by female proportion was positively correlated with total fat intake and negatively correlated with carbohydrate intake. Comparisons between participants with IBS and controls showed significantly lower fiber intake in participants with IBS with high heterogeneity (MD: -1.8; 95% CI: -3.0, -0.6; I2 = 85%). CONCLUSIONS AND INFERENCES: This review suggests that fiber and vitamin D intake is suboptimal in IBS; however, overall dietary intake does not appear to be comprised. Causes and consequences of reduced fiber in IBS deserve further study. Results of this systematic review and meta-analysis suggest that fiber and vitamin D intake is suboptimal in IBS. However, overall intake of other macro- and micronutrients does not appear to be compromised. Causes and consequences of reduced fiber and Vitamin D intake in IBS deserve further study.

Indexed as

Irritable Bowel SyndromeAdultDietEatingEnergy IntakeFemaleHumansVitamin DVitamin Denergyfiberfunctional GI disordersmacronutrientsmicronutrients

Identifiers

PMID37897138
PMCPMC10963049
OpenAlexW4387996564

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.