Evidence map›Paper›PMID 37896993›Full record

ArticleVaccines2023

Attitudes towards Vaccinations in a National Italian Cohort of Patients with Inflammatory Bowel Disease.

Andrea Costantino, Marco Michelon, Daniele Noviello, Fabio Salvatore Macaluso, Salvo Leone, Nicole Bonaccorso, Claudio Costantino, Maurizio Vecchi, Flavio Caprioli, AMICI Scientific Board

Open access · goldAbstract read
In one paragraph

Article in Vaccines, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Andrea CostantinoGastroenterology and Endoscopy Unit, Foundation IRCCS Ca' Granda Ospedale Maggiore Policlinico, 20122 Milan, Italy.ORCID 0000-0003-4345-6051
Marco MichelonDepartment of Pathophysiology and Transplantation, University of Milan, 20122 Milan, Italy.ORCID 0000-0002-9522-9814
Daniele NovielloDepartment of Pathophysiology and Transplantation, University of Milan, 20122 Milan, Italy.ORCID 0000-0002-3482-0109
Fabio Salvatore MacalusoIBD Unit, Villa Sofia-Cervello Hospital, 90146 Palermo, Italy.
Salvo LeoneAMICI ETS, 20125 Milan, Italy.ORCID 0000-0003-1690-8147
Nicole BonaccorsoDepartment of Health Promotion Sciences-Maternal and Infant Care-Internal Medicine and Excellence Specialties "G. D'Alessandro", University of Palermo, 90127 Palermo, Italy.ORCID 0000-0002-8021-8151
Claudio CostantinoDepartment of Health Promotion Sciences-Maternal and Infant Care-Internal Medicine and Excellence Specialties "G. D'Alessandro", University of Palermo, 90127 Palermo, Italy.ORCID 0000-0002-3397-7331
Maurizio VecchiGastroenterology and Endoscopy Unit, Foundation IRCCS Ca' Granda Ospedale Maggiore Policlinico, 20122 Milan, Italy.
Flavio CaprioliGastroenterology and Endoscopy Unit, Foundation IRCCS Ca' Granda Ospedale Maggiore Policlinico, 20122 Milan, Italy.
AMICI Scientific Board
University of Milan · ITUniversity of Palermo · ITOspedale Vincenzo Cervello · IT

Funding

Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico Current research
6 · The paper itself

Abstract

backgroundThe vaccination status of patients with inflammatory bowel disease (IBD) should be investigated before starting any treatment, and patients should eventually be vaccinated against vaccine-preventable diseases (VPDs). Patients with IBD may have suboptimal vaccination rates. The aim of this study was to evaluate the vaccination coverage, attitude towards vaccinations, and determinants among an Italian cohort of patients with IBD.

methodsAMICI, the Italian IBD patients' association, sent an anonymous web-based questionnaire in February 2021. Previous vaccination status and patients' attitudes towards vaccinations were recorded. We examined the factors influencing their attitudes using crude and adjusted odds ratios (adjORs) with 95% confidence intervals (CIs).

resultsAmong the 4039 patients invited, 1252 patients (including 729 women, median age 47.7 [37-58]) completed the questionnaire, with a response rate of 25.3%. Respondents declared being vaccinated against tetanus (74.1%), flu (67.7%; last season), MMR (43.3%), HBV (37.1%), pneumococcus (29.1%), meningitis (20%), HAV (16%), VZV (15.3%), and HPV (7.6%). Complete vaccination history was not remembered by 20.7% of the patients. One thousand one hundred and twelve (88.8%) expressed a positive attitude towards vaccination, 91 (7.3%) were indifferent, and 49 (3.9%) reported being opposed to vaccinations. The belief of a possible return of VPDs with a decline in vaccination coverage rates was the factor most strongly related to a positive attitude towards vaccinations (adjOR 5.67, 95% CI 3.45-9.30,

conclusionsA low vaccination rate against some VPDs was found among a national cohort of patients with IBD, despite a generally positive attitude towards vaccinations.

Indexed as

Crohn’s diseaseIBDinflammatory bowel diseaseulcerative colitisvaccinationvaccinevaccine hesitancyVZV

Identifiers

PMID37896993
PMCPMC10611209
OpenAlexW4387638387

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.