Evidence map›Paper›PMID 37896970›Full record

ArticleVaccines2023

Real-World Effectiveness of the Varicella Vaccine among Children and Adolescents in Qatar: A Case-Control Study.

Zahra Bibi, Ahmed Daniyal Nawaz, Maha Al Kurbi, Shahad Fakhroo, Khaled Ferih, Noor Al-Jaber, Merin Alex, Khalid H Elawad, Tawanda Chivese, Susu M Zughaier

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Vaccines, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
2.1field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 10 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Zahra BibiCollege of Medicine, QU Health, Qatar University, Doha P.O. Box 2713, Qatar.
Ahmed Daniyal NawazCollege of Medicine, QU Health, Qatar University, Doha P.O. Box 2713, Qatar.ORCID 0000-0001-9424-2665
Maha Al KurbiCollege of Medicine, QU Health, Qatar University, Doha P.O. Box 2713, Qatar.
Shahad FakhrooCollege of Medicine, QU Health, Qatar University, Doha P.O. Box 2713, Qatar.
Khaled FerihCollege of Medicine, QU Health, Qatar University, Doha P.O. Box 2713, Qatar.
Noor Al-JaberCollege of Medicine, QU Health, Qatar University, Doha P.O. Box 2713, Qatar.
Merin AlexHealth Protection, Primary Health Care Corporation (PHCC), Doha P.O. Box 26555, Qatar.
Khalid H ElawadHealth Protection, Primary Health Care Corporation (PHCC), Doha P.O. Box 26555, Qatar.ORCID 0000-0001-5362-3373
Tawanda ChiveseCollege of Medicine, QU Health, Qatar University, Doha P.O. Box 2713, Qatar.ORCID 0000-0001-6621-6144
Susu M ZughaierCollege of Medicine, QU Health, Qatar University, Doha P.O. Box 2713, Qatar.ORCID 0000-0001-7487-8770
Qatar University · QAPrimary Health Care · QA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDespite the availability of a highly efficacious vaccine, varicella outbreaks are still being reported globally. In this study, we evaluated the real-world effectiveness of varicella vaccination among children between the ages of 1 and 18 years old during the period 2017 to 2019 in Qatar.

methodsA matched case-control study was conducted that included all reported varicella-infected children who visited the primary healthcare system in Qatar from January 2017 to December 2019. The cases were children under the age of 18 years who were clinically diagnosed with varicella. The controls were of the same age, who visited the Primary Health Care Corporation (PHCC) during 2017-2019 with a skin rash where varicella infection was ruled out. The data on varicella vaccination for each participant were obtained from the electronic database in the PHCC during the study period.

resultsWe included 862 cases of varicella and 5454 matched controls, with a median age of 8 years (IQR 3-12); 47.4% were female and almost 50% were of Qatari nationality. The year 2019 had the highest varicella infection count with a total of 416 cases. The cases were less likely to be vaccinated against varicella, with approximately a quarter (25.6%) of cases and 36.7% of the controls having either one or two doses of the vaccine (

conclusionIn this multicultural setting, a two-dose varicella vaccination shows reasonable protection against varicella infection.

Indexed as

chickenpoxQatarvaccine effectivenessvaricella vaccinationvaricella-zoster virus

Identifiers

PMID37896970
PMCPMC10611158
OpenAlexW4387376573

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.