Evidence map›Paper›PMID 37896957›Full record

ArticleVaccines2023

Metabolic Syndrome Is Associated with Poor Omicron Infection Prognosis While Inactivated Vaccine Improves the Outcome of Coronavirus Disease 2019 among Chinese Inhabitants: A Retrospective Observational Study from a Chinese Municipality.

Ying Liu, Dong Chen, Junfeng Li, Wei Wang, Rongfeng Han, Shanshan Cui, Suqing Bao

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Vaccines, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.6field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Ying LiuEndocrinology Department, Tianjin First Central Hospital, Nankai University, Tianjin 300192, China.
Dong ChenGraduate School, Beijing Hospital of Traditional Chinese Medicine, Capital Medical University, Beijing 100010, China.ORCID 0000-0002-7692-7529
Junfeng LiEndocrinology Department, Tianjin First Central Hospital, Nankai University, Tianjin 300192, China.
Wei WangEndocrinology Department, Tianjin First Central Hospital, Nankai University, Tianjin 300192, China.
Rongfeng HanEndocrinology Department, Tianjin First Central Hospital, Nankai University, Tianjin 300192, China.
Shanshan CuiEndocrinology Department, Tianjin First Central Hospital, Nankai University, Tianjin 300192, China.
Suqing BaoEndocrinology Department, Tianjin First Central Hospital, Nankai University, Tianjin 300192, China.
Nankai University · CNCapital Medical University · CN

Funding

National Natural Science Foundation of China 81370977
6 · The paper itself

Abstract

Coronavirus disease 2019 (COVID-19) and metabolic syndrome (MetS) are currently highly prevalent diseases worldwide. Studies on clinical outcomes of patients with Omicron and MetS, especially after vaccination with an inactivated vaccine are limited. Herein, we explored the relationship between MetS and the outcome of Omicron infection. STUDY

designThis was a retrospective observational study.

methodsThis study recruited 316 individuals with Omicron infection. The inpatient data from between 8 January and 7 February 2022 were obtained from designated isolation hospitals in Tianjin, China. Hierarchical and multivariable analysis was conducted on age, gender, number of complications, and vaccination status.

resultsAmong the 316 study participants, 35.1% were diagnosed with MetS. The results showed that MetS was strongly associated with Intensive Unit Care (ICU) admission, Polymerase Chain Reaction (PCR) re-positivity, and severe COVID-19. The ICU admission rates of the unvaccinated individuals, those who received two-dose and full vaccination (3 doses), were 66.7%, 19.2%, and 0, respectively (

conclusionsIn summary, MetS increases the risk of ICU admission, PCR re-positivity, and severe COVID-19. MetS is a composite predictor of poor outcomes of Omicron infection. Two shots of inactivated vaccine, specifically three doses, effectively protect against Omicron even in the high-risk group.

Indexed as

COVID-19COVID-19 severityinactivated vaccinesMetSOmicron

Identifiers

PMID37896957
PMCPMC10611402
OpenAlexW4387234828

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.