Evidence map›Paper›PMID 37896926›Full record

ArticleVaccines2023

Pfizer-BioNTech mRNA Vaccine Protection among Children and Adolescents Aged 12-17 Years against COVID-19 Infection in Qatar.

Khadieja Osman, Jesha Mundodan, Juel Chowdhury, Rejoice Ravi, Rekayahouda Baaboura, Jeevan Albuquerque, Bilal Riaz, Reem Yusuf Emran, Khatija Batoul, Abdul Mahmood Esameldin and 3 more

Abstract read
In one paragraph

Article in Vaccines, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Khadieja OsmanNational COVID-19 Track & Trace Team, Ministry of Public Health, Doha P.O. Box 42, Qatar.
Jesha MundodanNational COVID-19 Track & Trace Team, Ministry of Public Health, Doha P.O. Box 42, Qatar.
Juel ChowdhuryNational COVID-19 Track & Trace Team, Ministry of Public Health, Doha P.O. Box 42, Qatar.
Rejoice RaviNational COVID-19 Track & Trace Team, Ministry of Public Health, Doha P.O. Box 42, Qatar.
Rekayahouda BaabouraNational COVID-19 Track & Trace Team, Ministry of Public Health, Doha P.O. Box 42, Qatar.
Jeevan AlbuquerqueNational COVID-19 Track & Trace Team, Ministry of Public Health, Doha P.O. Box 42, Qatar.
Bilal RiazNational COVID-19 Track & Trace Team, Ministry of Public Health, Doha P.O. Box 42, Qatar.
Reem Yusuf EmranNational COVID-19 Track & Trace Team, Ministry of Public Health, Doha P.O. Box 42, Qatar.
Khatija BatoulNational COVID-19 Track & Trace Team, Ministry of Public Health, Doha P.O. Box 42, Qatar.
Abdul Mahmood EsameldinNational COVID-19 Track & Trace Team, Ministry of Public Health, Doha P.O. Box 42, Qatar.
Zinah Al TabatabaeeNational COVID-19 Track & Trace Team, Ministry of Public Health, Doha P.O. Box 42, Qatar.
Hayat KhogaliNational COVID-19 Track & Trace Team, Ministry of Public Health, Doha P.O. Box 42, Qatar.ORCID 0000-0002-2522-2035
Soha AlbayatNational COVID-19 Track & Trace Team, Ministry of Public Health, Doha P.O. Box 42, Qatar.ORCID 0000-0002-5302-3455

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Qatar was also hit hard by the global pandemic of SARS-CoV-2, with the original virus, Alpha variant, Beta variant, Omicron BA.1 and BA.2 variants, Omicron BA.4 and BA.5 variants, and Delta variant, sequentially. The two-dose primary series of BNT162b2 (Pfizer-BioNTech) COVID-19 vaccine against SARS-CoV-2 infection has been approved for use in 30 µg formulations among children and adolescents aged 12-17 years as of 16 May 2021. This study aimed at estimating the effectiveness of the 30 µg BNT162b2 Pfizer-BioNTech mRNA COVID-19 vaccine against the pre-Omicron variants of SARS-CoV-2 infection in children and adolescents aged 12-17 years residing in Qatar. A test-negative matched case-control study was conducted. The subjects included any child or adolescent aged 12-17 years who had been tested for SARS-CoV-2 using RT-PCR tests performed on nasopharyngeal or oropharyngeal swabs, as part of contact tracing, between June and November 2021, and was eligible to receive the BNT162b2 vaccine as per the national guidelines. Data regarding 14,161 children/adolescents meeting inclusion-exclusion criteria were retrieved from the national Surveillance and Vaccine Electronic System (SAVES). Of the total, 3.1% (444) were positive for SARS-CoV-2. More than half (55.96%) were vaccinated with two doses of Pfizer-BioNTech-mRNA COVID-19 vaccine. Amongst those immunized with two doses, 1.2% tested positive for SARS-CoV-2, while 5.6% amongst the unvaccinated tested positive. The vaccine effectiveness was calculated to be 79%. Pfizer-BioNTech mRNA COVID-19 vaccine provides protection from COVID-19 infection for children/adolescents; hence, it is crucial to ensure they receive the recommended vaccines.

Indexed as

12–17 years COVID-19 vaccineadolescentBNT162b2childrenfully vaccinatedpartially vaccinatedPfizerRT-PCR-positivevaccination statusvaccine effectiveness

Identifiers

PMID37896926
PMCPMC10610824

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.