Evidence map›Paper›PMID 37896916›Full record

ArticleVaccines2023

Association between Vaccination Status for COVID-19 and the Risk of Severe Symptoms during the Endemic Phase of the Disease.

Oliver Mendoza-Cano, Xóchitl Trujillo, Mónica Ríos-Silva, Agustin Lugo-Radillo, Verónica Benites-Godínez, Jaime Alberto Bricio-Barrios, Herguin Benjamin Cuevas-Arellano, Eder Fernando Ríos-Bracamontes, Walter Serrano-Moreno, Yolitzy Cárdenas and 1 more

Open access · goldAbstract read
In one paragraph

Article in Vaccines, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.8field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Oliver Mendoza-CanoFacultad de Ingeniería Civil, Universidad de Colima, km. 9 Carretera Colima-Coquimatlán, Coquimatlán 28400, Mexico.ORCID 0000-0001-9614-4946
Xóchitl TrujilloCentro Universitario de Investigaciones Biomédicas, Universidad de Colima, Av. 25 de Julio 965, Colima 28045, Mexico.ORCID 0000-0001-8146-5667
Mónica Ríos-SilvaCONAHCyT-Centro Universitario de Investigaciones Biomédicas, Universidad de Colima, Av. 25 de Julio 965, Colima 28045, Mexico.ORCID 0000-0002-2883-4619
Agustin Lugo-RadilloCONAHCyT-Faculty of Medicine and Surgery, Universidad Autónoma Benito Juárez de Oaxaca, Ex Hacienda Aguilera S/N, Carr. a San Felipe del Agua, Oaxaca 68020, Mexico.ORCID 0000-0001-6689-2783
Verónica Benites-GodínezCoordinación de Educación en Salud, Instituto Mexicano del Seguro Social, Calzada del Ejercito Nacional 14, Tepic 63169, Mexico.
Jaime Alberto Bricio-BarriosFacultad de Medicina, Universidad de Colima, Av. Universidad 333, Colima 28040, Mexico.ORCID 0000-0001-5667-5179
Herguin Benjamin Cuevas-ArellanoFacultad de Ciencias, Universidad de Colima, Bernal Díaz del Castillo 340, Colima 28045, Mexico.ORCID 0009-0003-0788-4312
Eder Fernando Ríos-BracamontesDepartamento de Medicina Interna, Hospital General de Zona No. 1, Instituto Mexicano del Seguro Social, Av. Lapislázuli 250, Villa de Álvarez 28984, Mexico.
Walter Serrano-MorenoFacultad de Medicina, Universidad de Colima, Av. Universidad 333, Colima 28040, Mexico.ORCID 0000-0003-2111-6371
Yolitzy CárdenasCentro Universitario de Investigaciones Biomédicas, Universidad de Colima, Av. 25 de Julio 965, Colima 28045, Mexico.ORCID 0000-0003-3070-1724
Efrén Murillo-ZamoraUnidad de Investigación en Epidemiología Clínica, Instituto Mexicano del Seguro Social, Av. Lapislázuli 250, Villa de Álvarez 28984, Mexico.ORCID 0000-0002-1118-498X
Universidad de Colima · MXMexican Social Security Institute · MXBenito Juárez Autonomous University of Oaxaca · MX

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The global health emergency caused by COVID-19 concluded in May 2023, marking the beginning of an endemic phase. This study aimed to evaluate the association between vaccination status and other patient characteristics and the risk of severe disease during this new endemic period. A nationwide cohort study was conducted in Mexico, where we analyzed data from 646 adults who had received positive confirmation of COVID-19 through PCR testing from May to August 2023. The overall risk of severe symptoms in the study sample was 5.3%. The average time elapsed from the last vaccine shot to symptom onset was over six months in all the immunized groups (1, 2 or 3 vaccine doses). Compared to unvaccinated patients, those with three vaccine doses showed an elevated risk of severe symptoms. Advancing age and various chronic comorbidities (specifically cardiovascular, kidney, and obstructive pulmonary conditions) were associated with a heightened risk of severe COVID-19 manifestations. These findings underscore the ongoing seriousness of COVID-19, even in an endemic phase, underscoring the urgent need for tailored interventions aimed at high-risk patients.

Indexed as

cohort studiesCOVID-19Mexicopolymerase chain reactionvaccines

Identifiers

PMID37896916
PMCPMC10610663
OpenAlexW4386996010

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.