Evidence map›Paper›PMID 37896827›Full record

ReviewViruses2023

RNAi-Based Therapy: Combating Shrimp Viral Diseases.

Md Shahanoor Alam, Mohammad Nazrul Islam, Mousumi Das, Sk Farzana Islam, Md Golam Rabbane, Ehsanul Karim, Animesh Roy, Mohammad Shafiqul Alam, Raju Ahmed, Abu Syed Md Kibria

Open access · goldAbstract readReview
In one paragraph

Review in Viruses, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
3.0field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 18 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. RNA silencing: the future potential strategy for engineering virus resistance in plants.Physiology and molecular biology of plants : an international journal of functional plant biology · 2025
    Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 6 institutions in 1 country.

Md Shahanoor AlamDepartment of Genetics and Fish Breeding, Bangabandhu Sheikh Mujibur Rahman Agricultural University, Gazipur 1706, Bangladesh.ORCID 0000-0002-7298-9562
Mohammad Nazrul IslamDepartment of Biotechnology, Sher-e-Bangla Agricultural University, Dhaka 1207, Bangladesh.
Mousumi DasDepartment of Aquaculture, Bangabandhu Sheikh Mujibur Rahman Agricultural University, Gazipur 1706, Bangladesh.ORCID 0000-0002-8142-0124
Sk Farzana IslamDepartment of Fisheries (DoF), Government of the People's Republic of Bangladesh, Matshya Bhaban, Ramna, Dhaka 1000, Bangladesh.
Md Golam RabbaneDepartment of Fisheries, Faculty of Biological Sciences, University of Dhaka, Dhaka 1000, Bangladesh.
Ehsanul KarimBangladesh Fisheries Research Institute, Mymensingh 2201, Bangladesh.
Animesh RoyDepartment of Fisheries Biology and Aquatic Environment, Bangabandhu Sheikh Mujibur Rahman Agricultural University, Gazipur 1706, Bangladesh.
Mohammad Shafiqul AlamDepartment of Genetics and Fish Breeding, Bangabandhu Sheikh Mujibur Rahman Agricultural University, Gazipur 1706, Bangladesh.ORCID 0000-0001-7910-1741
Raju AhmedDepartment of Fisheries (DoF), Government of the People's Republic of Bangladesh, Matshya Bhaban, Ramna, Dhaka 1000, Bangladesh.
Abu Syed Md KibriaDepartment of Aquaculture, Hajee Mohammad Danesh Science and Technology University, Dinajpur 5200, Bangladesh.
Gazipur Agricultural University · BDPeople's University of Bangladesh · BDBangladesh Fisheries Research Institute · BDHajee Mohammad Danesh Science and Technology University · BDSher-e-Bangla Agricultural University · BDUniversity of Dhaka · BD

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Shrimp aquaculture has become a vital industry, meeting the growing global demand for seafood. Shrimp viral diseases have posed significant challenges to the aquaculture industry, causing major economic losses worldwide. Conventional treatment methods have proven to be ineffective in controlling these diseases. However, recent advances in RNA interference (RNAi) technology have opened new possibilities for combating shrimp viral diseases. This cutting-edge technology uses cellular machinery to silence specific viral genes, preventing viral replication and spread. Numerous studies have shown the effectiveness of RNAi-based therapies in various model organisms, paving the way for their use in shrimp health. By precisely targeting viral pathogens, RNAi has the potential to provide a sustainable and environmentally friendly solution to combat viral diseases in shrimp aquaculture. This review paper provides an overview of RNAi-based therapy and its potential as a game-changer for shrimp viral diseases. We discuss the principles of RNAi, its application in combating viral infections, and the current progress made in RNAi-based therapy for shrimp viral diseases. We also address the challenges and prospects of this innovative approach.

Indexed as

RNAi TherapeuticsVirus DiseasesAnimalsAquacultureCrustaceaRNA InterferencedsRNAinnate immune responsepenaeid shrimppost-transcriptional gene silencingshrimp viral diseasessiRNAtherapeutics

Identifiers

PMID37896827
PMCPMC10612085
OpenAlexW4387375993

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.