Evidence map›Paper›PMID 37896798›Full record

ArticleViruses2023

Evidence of Circulation and Phylogenetic Analysis of Hepatitis E Virus (HEV) in Wild Boar in South-East Italy.

Gianfranco La Bella, Maria Grazia Basanisi, Gaia Nobili, Rosa Coppola, Annita Maria Damato, Adelia Donatiello, Gilda Occhiochiuso, Antonella Cristina Romano, Mariateresa Toce, Lucia Palazzo and 7 more

Open access · goldAbstract read
In one paragraph

Article in Viruses, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
2.2field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.

  1. Pooled it
  2. Genetic Heterogeneity of Hepatitis E Virus (HEV) in Wild Boars in Italy.Animals : an open access journal from MDPI · 2026
    Article
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  4. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 4 institutions in 1 country.

Gianfranco La BellaIstituto Zooprofilattico Sperimentale della Puglia e della Basilicata, 71121 Foggia, Italy.ORCID 0000-0003-3557-1439
Maria Grazia BasanisiIstituto Zooprofilattico Sperimentale della Puglia e della Basilicata, 71121 Foggia, Italy.ORCID 0000-0001-8103-383X
Gaia NobiliIstituto Zooprofilattico Sperimentale della Puglia e della Basilicata, 71121 Foggia, Italy.ORCID 0000-0003-3898-1644
Rosa CoppolaIstituto Zooprofilattico Sperimentale della Puglia e della Basilicata, 71121 Foggia, Italy.
Annita Maria DamatoIstituto Zooprofilattico Sperimentale della Puglia e della Basilicata, 71121 Foggia, Italy.
Adelia DonatielloIstituto Zooprofilattico Sperimentale della Puglia e della Basilicata, 71121 Foggia, Italy.ORCID 0000-0002-5251-2150
Gilda OcchiochiusoIstituto Zooprofilattico Sperimentale della Puglia e della Basilicata, 71121 Foggia, Italy.
Antonella Cristina RomanoIstituto Zooprofilattico Sperimentale della Puglia e della Basilicata, 71121 Foggia, Italy.ORCID 0000-0002-2634-9054
Mariateresa ToceIstituto Zooprofilattico Sperimentale della Puglia e della Basilicata, 71121 Foggia, Italy.
Lucia PalazzoIstituto Zooprofilattico Sperimentale della Puglia e della Basilicata, 71121 Foggia, Italy.
Francesco PellegriniDepartment of Veterinary Medicine, University of Bari Aldo Moro, 70010 Bari, Italy.ORCID 0000-0003-0026-8472
Angela FanelliDepartment of Veterinary Medicine, University of Bari Aldo Moro, 70010 Bari, Italy.ORCID 0000-0002-8204-1230
Barbara Di MartinoDepartment of Veterinary Medicine, Università degli Studi di Teramo, 64100 Teramo, Italy.ORCID 0000-0001-6192-7166
Elisabetta SuffrediniDepartment of Food Safety Nutrition and Veterinary Public Health, Istituto Superiore di Sanità, 00161 Rome, Italy.ORCID 0000-0001-7605-0539
Gianvito LanaveDepartment of Veterinary Medicine, University of Bari Aldo Moro, 70010 Bari, Italy.ORCID 0000-0003-4614-677X
Vito MartellaDepartment of Veterinary Medicine, University of Bari Aldo Moro, 70010 Bari, Italy.ORCID 0000-0002-5740-6947
Giovanna La SalandraIstituto Zooprofilattico Sperimentale della Puglia e della Basilicata, 71121 Foggia, Italy.
Istituto Zooprofilattico Sperimentale della Puglia e della Basilicata · ITUniversity of Bari Aldo Moro · ITIstituto Superiore di Sanità · ITUniversity of Teramo · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hepatitis E virus (HEV) is an important cause of acute viral hepatitis in humans worldwide. The food-borne transmission of HEV appears to be a major route in Europe through the consumption of pork and wild boar meat. HEV epidemiology in wild boars has been investigated mainly in Northern and Central Italian regions, whilst information from Southern Italy is limited. We investigated the occurrence of HEV in wild boar in the Apulia and Basilicata regions (Southern Italy). Thirteen (10.4%) out of one hundred and twenty-five wild boar samples tested positive for HEV using a quantitative reverse transcription PCR. HEV prevalence was 12% in Apulia and 9.3% in Basilicata. Seven samples were genotyped, and different subtypes (c, f, m) of genotype 3 were identified. The complete genome of a 3m strain was determined, and the virus showed the highest nucleotide identity to a human HEV strain identified in France in 2017. These findings demonstrate the substantial circulation of HEV in the wild boar population in Italian Southern regions. Gathering information on the HEV strains circulating in different geographical areas is useful for tracking the origin of HEV outbreaks and assessing the epidemiological role of wild boar as a potential virus reservoir for domestic pigs.

Indexed as

Hepatitis EHepatitis E virusSwine DiseasesAnimalsHumansItalyPhylogenyRNA, ViralSus scrofaSwineRNA, Viralhepatitis E viruspublic healthwhole genomewild boarzoonosis

Identifiers

PMID37896798
PMCPMC10611066
OpenAlexW4387180609

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.