Evidence map›Paper›PMID 37896766›Full record

ArticleViruses2023

Hybrid Immunity Results in Enhanced and More Sustained Antibody Responses after the Second Sinovac-CoronaVac Dose in a Brazilian Cohort: DETECTCoV-19 Cohort.

Bárbara Batista Salgado, Aguyda Rayany Cavalcante Barbosa, Ana Ruth Arcanjo, Daniel Barros de Castro, Tatyana Costa Amorim Ramos, Felipe Naveca, Daniel M Altmann, Rosemary J Boyton, Jaila Dias Borges Lalwani, Pritesh Lalwani

Open access · goldAbstract read
In one paragraph

Article in Viruses, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Antibody Response in Healthcare Workers During the SARS-CoV-2 Gamma Variant Outbreak in Manaus, Brazil.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2025
    Observational
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 2 countries.

Bárbara Batista SalgadoInstituto Leônidas e Maria Deane (ILMD), Fiocruz Amazônia, Rua Terezina, 476 Adrianópolis, Manaus 69057-070, AM, Brazil.
Aguyda Rayany Cavalcante BarbosaInstituto Leônidas e Maria Deane (ILMD), Fiocruz Amazônia, Rua Terezina, 476 Adrianópolis, Manaus 69057-070, AM, Brazil.
Ana Ruth ArcanjoFundação de Vigilância em Saúde do Amazonas (FVS/AM), Manaus 69093-018, AM, Brazil.
Daniel Barros de CastroFundação de Vigilância em Saúde do Amazonas (FVS/AM), Manaus 69093-018, AM, Brazil.
Tatyana Costa Amorim RamosFundação de Vigilância em Saúde do Amazonas (FVS/AM), Manaus 69093-018, AM, Brazil.
Felipe NavecaInstituto Leônidas e Maria Deane (ILMD), Fiocruz Amazônia, Rua Terezina, 476 Adrianópolis, Manaus 69057-070, AM, Brazil.ORCID 0000-0002-2888-1060
Daniel M AltmannDepartment of Immunology and Inflammation, Imperial College London, London W12 0NN, UK.ORCID 0000-0002-2436-6192
Rosemary J BoytonLung Division, Royal Brompton and Harefield Hospitals, Guy's and St Thomas' NHS Foundation Trust, London SW3 6LY, UK.
Jaila Dias Borges LalwaniLaboratory of Infectious Diseases and Immunology, ILMD/Fiocruz Amazônia and PPGIBA/ICB-UFAM, Manaus 69080-900, AM, Brazil.ORCID 0000-0002-8310-4264
Pritesh LalwaniInstituto Leônidas e Maria Deane (ILMD), Fiocruz Amazônia, Rua Terezina, 476 Adrianópolis, Manaus 69057-070, AM, Brazil.ORCID 0000-0003-2996-0446
Universidade Federal do Amazonas · BRFundação de Medicina Tropical · BRGuy's and St Thomas' NHS Foundation Trust · GBImperial College London · GB

Funding

Coronavirus Aid, Relief, and Economic Security Act (CARES) NU2GGH002174/0900F3EB81EE4293Medical Research Council MR/W020610/1
6 · The paper itself

Abstract

We measured anti-SARS-CoV-2 antibody responses before and after CoronaVac (inactivated) vaccination in a case-control study performed in CoronaVac-immunized individuals participating in a longitudinal prospective study of adults in Manaus (DETECTCoV-19). Antibody responses were measured by standard serological immunoassays. Peak anti-S-RBD and neutralizing RBD-ACE2 blocking antibody responses after two doses of CoronaVac vaccine were similar in vaccine breakthrough cases (

Indexed as

Angiotensin-Converting Enzyme 2Antibody FormationAdultAntibodies, NeutralizingAntibodies, ViralBrazilCase-Control StudiesCOVID-19 VaccinesHumansProspective StudiesVaccines, InactivatedAngiotensin-Converting Enzyme 2Antibodies, NeutralizingAntibodies, ViralCOVID-19 Vaccinessinovac COVID-19 vaccineVaccines, Inactivatedantibody responsebreakthroughCoronaVacSARS-CoV-2vaccine

Identifiers

PMID37896766
PMCPMC10610994
OpenAlexW4386997510

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.