Evidence map›Paper›PMID 37896757›Full record

Observational studyViruses2023

Retention in Care and Virological Failure among Adult HIV-Positive Patients on First-Line Antiretroviral Treatment in Maputo, Mozambique.

Leonid Joaquim, Mafalda N S Miranda, Victor Pimentel, Maria do Rosario Oliveira Martins, Tacilta Nhampossa, Ana Abecasis, Marta Pingarilho

Open access · goldAbstract readObservational Study
In one paragraph

Observational study in Viruses, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 8 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Leonid JoaquimCentro Integrado de Cuidados e Tratamento, Hospital Militar de Maputo, Maputo P.O. Box 21414368/9, Mozambique.ORCID 0000-0001-6194-4193
Mafalda N S MirandaGlobal Health and Tropical Medicine (GHTM), Associate Laboratory in Translation and Innovation Towards Global Health (LA-REAL), Instituto de Higiene e Medicina Tropical (IHMT), Universidade NOVA de Lisboa (UNL), Rua da Junqueira 100, 1349-008 Lisboa, Portugal.
Victor PimentelGlobal Health and Tropical Medicine (GHTM), Associate Laboratory in Translation and Innovation Towards Global Health (LA-REAL), Instituto de Higiene e Medicina Tropical (IHMT), Universidade NOVA de Lisboa (UNL), Rua da Junqueira 100, 1349-008 Lisboa, Portugal.
Maria do Rosario Oliveira MartinsGlobal Health and Tropical Medicine (GHTM), Associate Laboratory in Translation and Innovation Towards Global Health (LA-REAL), Instituto de Higiene e Medicina Tropical (IHMT), Universidade NOVA de Lisboa (UNL), Rua da Junqueira 100, 1349-008 Lisboa, Portugal.ORCID 0000-0002-7941-0285
Tacilta NhampossaCentro de Investigação em Saúde de Manhiça, Sede, Manhiça, Rua 12, Maputo 1929, Mozambique.
Ana AbecasisGlobal Health and Tropical Medicine (GHTM), Associate Laboratory in Translation and Innovation Towards Global Health (LA-REAL), Instituto de Higiene e Medicina Tropical (IHMT), Universidade NOVA de Lisboa (UNL), Rua da Junqueira 100, 1349-008 Lisboa, Portugal.ORCID 0000-0002-3903-5265
Marta PingarilhoGlobal Health and Tropical Medicine (GHTM), Associate Laboratory in Translation and Innovation Towards Global Health (LA-REAL), Instituto de Higiene e Medicina Tropical (IHMT), Universidade NOVA de Lisboa (UNL), Rua da Junqueira 100, 1349-008 Lisboa, Portugal.ORCID 0000-0002-7928-3087
Universidade Nova de Lisboa · PTManhiça Health Research Centre · MZMaputo Central Hospital · MZ

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionAccess to antiretroviral treatment (ART) is increasingly available worldwide; however, the number of patients lost to follow-up and number of treatment failures continue to challenge most African countries.

objectivesTo analyse the retention in clinical care and the virological response and their associated factors of HIV-1 patients from the Maputo Military Hospital (MMH).

methodsA cross-sectional observational study was conducted to analyse data from patients who started ART between 2016 and 2018 in the MMH.

resultsAt the end of 12 months, 75.1% of 1247 patients were active on clinical follow-up and 16.8% had suspected virologic failure (VL > 1000 copies/mm

conclusionsWe have identified clinical and sociodemographic determinants of loss to follow-up and in the development of virological failure for HIV-positive patients in clinical care in the MMH. Therefore, HIV programs must consider these factors to increase the screening of patients at high risk of poor outcomes and particularly to strengthen adherence counselling programs.

Indexed as

Anti-HIV AgentsHIV InfectionsRetention in CareAdultAnti-Retroviral AgentsCD4 Lymphocyte CountCross-Sectional StudiesHumansMiddle AgedMozambiqueTreatment FailureViral LoadAnti-HIV AgentsAnti-Retroviral AgentsHIV-1Mozambiqueretention on carevirological response

Identifiers

PMID37896757
PMCPMC10610786
OpenAlexW4386996719

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.